Advances in Adhesive Dentistry: From Fundamental Mechanisms to Clinical Applications

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Background

Adhesive dentistry has revolutionized restorative and preventive dental care by enabling minimally invasive treatments and long-lasting restorations. Understanding the mechanisms of adhesion to enamel, dentin, and novel restorative materials is crucial for optimizing clinical outcomes. Despite the advances in adhesive formulations and application protocols, challenges remain regarding bond durability, interface degradation, and material biocompatibility. Emerging strategies, such as bioactive adhesives, nanoparticle incorporation, and surface treatments for 3D-printed resins, offer promising solutions to these challenges. This Research Topic aims to consolidate cutting-edge research that bridges fundamental adhesive science with clinical practice, highlighting innovations that improve bond strength, longevity, and patient outcomes.

The primary goal of this Research Topic is to provide a comprehensive platform for high-quality research and reviews focused on adhesive dentistry. We seek contributions that address the persistent challenges of achieving durable and reliable adhesion in restorative procedures, including degradation of the hybrid layer, material instability, and failure under clinical conditions. The issue will also explore innovations in adhesive formulations, surface treatment protocols, and bioactive material incorporation, including advances in resin-modified glass ionomers, nanoparticle-enhanced adhesives, and 3D-printed restorative surfaces. By compiling research that integrates laboratory-based mechanistic studies with clinical evaluations, this issue aims to promote evidence-based practices, inspire future innovation, and guide the development of adhesive materials and protocols that maximize restoration longevity, enhance patient safety, and advance the field of restorative dentistry as a whole.

This Research Topic invites contributions that explore all aspects of adhesive dentistry, from fundamental mechanisms to clinical applications. Specific themes of interest include: bond formation and degradation at the enamel and dentin interface, hybrid layer characterization, surface treatments for conventional and 3D-printed resins, bioactive and nanoparticle-enhanced adhesives, resin-modified glass ionomers, and long-term clinical outcomes of adhesive restorations. We particularly welcome studies that integrate laboratory-based mechanistic investigations with clinical evaluations to advance evidence-based practices. Manuscripts may include original research articles, systematic reviews, meta-analyses, methodological studies, case reports demonstrating novel adhesive techniques, and perspectives on emerging technologies in adhesion. Authors are encouraged to submit high-quality work that contributes to improving the durability, biocompatibility, and clinical effectiveness of adhesive materials and protocols in restorative dentistry.

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Keywords: adhesive dentistry, enamel dentin adhesion, hybrid layer durability, bond strength longevity, bioactive dental adhesives, nanoparticle-enhanced adhesives, resin-modified glass ionomer, 3d-printed resin surface treatment

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