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Computational Integration of Single-Cell Omics and Genetics for Disease Mechanisms

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ORIGINAL RESEARCH

Published on 28 Sep 2026

Alzheimer’s disease diagnosis based on gene selection and cross-tissue validation

Xiaolan Zhang
Xiaotong Tang
Qian Bo
Yu Ma
Fang Shi
Hongpeng Hou

doi 10.3389/fgene.2026.1890236

696 views

ORIGINAL RESEARCH

Published on 08 Jun 2026

LAIOR: a hyperbolic neural ODE variational framework for interpretable single-cell manifold learning and trajectory inference

Zeyu Fu
Jiawei Fu
Keyang Zhang
Tianfei Ran
Chunlin Chen

doi 10.3389/fgene.2026.1838613

2,003 views

ORIGINAL RESEARCH

Published on 05 Jun 2026

SIGMA: self-supervised inference of gene networks via masked auto-encoding

Qian Wang
Ziyi Zhang
Nan-Qing Liao
Shibin Yang
Zehua He

doi 10.3389/fgene.2026.1825728

1,416 views

ORIGINAL RESEARCH

Accepted on 13 Oct 2026

Integrated single-cell and bulk transcriptomic analyses reveal UTF1-associated spermatogenic dysfunction and identify ACTRT2 and AKAP4 as biomarkers in non-obstructive azoospermia

Jin Yu
Mingming Li
Zhou Yue
Hekun Liu
Chengbin Pei
Lianghong Ma

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Frontiers in Genetics

Frontiers in Genetics

Computational Genomics

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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