Checkpoint immunotherapy: Reshaping the landscape of gastrointestinal cancer treatment - Volume III

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Articles

SYSTEMATIC REVIEW

Published on 25 Sep 2026

Impact of immune checkpoint inhibitors as neoadjuvant/perioperative therapy for locally advanced resectable gastric/gastroesophageal junction adenocarcinoma: a systematic review and meta-analysis

Zhengyi Chen
Xin Liu
Hanling Sun
Nini Cao
Junlin Zhou
Zihan Chen
Yang Song
Jun Yao

doi 10.3389/fimmu.2026.1909466

652 views

SYSTEMATIC REVIEW

Published on 03 Sep 2026

Overall survival with immune checkpoint inhibitors across treatment settings and clinical and PD-L1-defined subgroups in advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis of randomized trials

Bing Wang
Xiaoyu Han
Zengli Shen

doi 10.3389/fimmu.2026.1901673

936 views

ORIGINAL RESEARCH

Published on 25 Aug 2026

Perioperative immunochemotherapy for resectable gastric or gastroesophageal junction cancer: a meta-analysis of efficacy and safety from randomized trials

Juan Xu
Xiao-mei Li
Chen Yang
Rui Zhang
Hai-lin Lyu
Li Wang
Jing Xie

doi 10.3389/fimmu.2026.1765780

911 views

SYSTEMATIC REVIEW

Published on 19 Aug 2026

The efficacy and safety of pembrolizumab in the treatment of HER2-negative advanced gastric or gastroesophageal junction cancer: a systematic review and meta-analysis of emerging clinical data

Ying Yang
Lingli Jiang
Genming Zhang
Ke Li
Daorui Li

doi 10.3389/fimmu.2026.1862751

1,265 views

SYSTEMATIC REVIEW

Published on 17 Aug 2026

Efficacy hierarchy and absolute survival benefit of first-line immunotherapy in advanced gastric cancer: a meta-analysis and pooled survival analysis

Jialun Lv
Krishnapriya Thangaretnam
Md Obaidul Islam
Jason Tang
Sabine Denize
Nadeem Bhat
Shoumin Zhu
Heng Lu
Dunfa Peng
1 more
Zheng Chen

doi 10.3389/fimmu.2026.1866848

1,032 views

REVIEW

Published on 09 Jul 2026

Efficacy and safety of neoadjuvant chemotherapy with immunotherapy versus chemotherapy alone in esophageal squamous cell carcinoma: a meta-analysis based on randomized controlled trials

Yibang Ye
Liangyu Zhang
Zhenyuan Yang
Yizhou Huang
Maohui Chen
Shuliang Zhang
Taidui Zeng
Chun Chen
Bin Zheng

doi 10.3389/fimmu.2026.1825905

1,182 views

REVIEW

Published on 01 Jul 2026

Optimizing immunotherapy in advanced gastric cancer: established and emerging biomarkers for precision patient selection

Xianjun Rao
Guodong Huang
Jiaxuan Li
Chunyu Wu
Min Yang
Xianfeng Rao
Zixing Qian
Liji Chen
Yang Yang
Wei Wei

doi 10.3389/fimmu.2026.1775386

1,735 views
2 citations

CASE REPORT

Published on 03 Jun 2026

Case Report: Multimodal management of duodenal metastasis from hepatocellular carcinoma complicated by intractable hemorrhage

Xin Zhang
Zhongsong Gao
Jiao Wang
Baiguo Xu
Bo Li
Bo Feng
Kefeng Jia

doi 10.3389/fimmu.2026.1785498

1,070 views
1 citation

CASE REPORT

Published on 01 May 2026

Case Report: Anti-PD-1 therapy as a catalyst for the rapid transformation of a hepatic nodule into HCC: a “soil and seed” paradox in metachronous triple primary malignancies?

Xian Yang
Dehua Kong
Boan Lai
Chuan Zhang
Na Li

doi 10.3389/fimmu.2026.1831238

1,351 views
1 citation

ORIGINAL RESEARCH

Accepted on 31 Jul 2026

Sintilimab Plus Fruquintinib Versus Fruquintinib Alone as Later-Line Therapy for Advanced Microsatellite-Stable Colorectal Cancer: A Single-Center Retrospective Cohort Study

Xiaoyue Fu
Yuan Gao
Jiaoxue He
Xiaodong Hu
Wanzhi Yao
Xiaoyan Le

400 views

SYSTEMATIC REVIEW

Accepted on 06 Oct 2026

PD-1/PD-L1 inhibitors in the treatment of pMMR mCRC: a meta-analysis based on randomized controlled trials

Sumin Lv
Chaoyue Ma
Zeqi Tang
Xinyan Zhang
Wen Shi
Shiyan Z
Minyuan Ni
Lihu Gu
Bangsheng Chen

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Cancer Immunity and Immunotherapy

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Frontiers in Oncology
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Articles

Impact of immune checkpoint inhibitors as neoadjuvant/perioperative therapy for locally advanced resectable gastric/gastroesophageal junction adenocarcinoma: a systematic review and meta-analysis

Overall survival with immune checkpoint inhibitors across treatment settings and clinical and PD-L1-defined subgroups in advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis of randomized trials

Perioperative immunochemotherapy for resectable gastric or gastroesophageal junction cancer: a meta-analysis of efficacy and safety from randomized trials

The efficacy and safety of pembrolizumab in the treatment of HER2-negative advanced gastric or gastroesophageal junction cancer: a systematic review and meta-analysis of emerging clinical data

Efficacy hierarchy and absolute survival benefit of first-line immunotherapy in advanced gastric cancer: a meta-analysis and pooled survival analysis

Efficacy and safety of neoadjuvant chemotherapy with immunotherapy versus chemotherapy alone in esophageal squamous cell carcinoma: a meta-analysis based on randomized controlled trials

Optimizing immunotherapy in advanced gastric cancer: established and emerging biomarkers for precision patient selection

Case Report: Multimodal management of duodenal metastasis from hepatocellular carcinoma complicated by intractable hemorrhage

Case Report: Anti-PD-1 therapy as a catalyst for the rapid transformation of a hepatic nodule into HCC: a “soil and seed” paradox in metachronous triple primary malignancies?

Sintilimab Plus Fruquintinib Versus Fruquintinib Alone as Later-Line Therapy for Advanced Microsatellite-Stable Colorectal Cancer: A Single-Center Retrospective Cohort Study

PD-1/PD-L1 inhibitors in the treatment of pMMR mCRC: a meta-analysis based on randomized controlled trials

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Other participating journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy