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Droplet Dynamics and Control in Microfluidic Platform for Enhanced System Design

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 30 November 2026

  2. This Research Topic is currently accepting articles

Background

Microfluidics is a rapidly evolving field that plays a crucial role in lab-on-a-chip technologies, chemical analysis, and biological diagnostics. One of the major challenges in microfluidic systems is achieving precise control over droplet behavior, which is influenced by flow conditions, fluid properties, including biological constituents, external fields (electrical, magnetic, acoustic, etc.), channel geometry, and surface physicochemical characteristics. Although significant advances in experimental and computational studies have been made over the past decade, a comprehensive understanding of droplet dynamics under these coupled effects still requires focused research efforts.

This Research Topic aims to explore the following specific areas and invites both experimental and computational contributions (original research article and review article) in the field, including but not limited to:



o Active and passive droplet sorting techniques

o Droplet generation using porous media and low-cost paper-based microfluidic platforms

o Electrohydrodynamic effects on droplet manipulation and control

o Acoustic-based droplet sorting and separation

o Nanoparticle synthesis and manufacturing using droplet microfluidics

o AI-driven droplet control and real-time microfluidic automation

o Droplet-based platforms for single-cell analysis

o Energy harvesting droplet systems

o Droplet applications in spheroid and organoid formation

o Droplet-based digital PCR

o Magnetic levitation of droplet for biological applications



This Research Topic welcomes research submissions in the forms of Original Research, Review, Mini Review & Opinion articles.

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Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Editorial
  • FAIR² Data
  • Mini Review
  • Opinion
  • Original Research
  • Perspective
  • Review

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: Microfluidics, Emulsion-based platforms, Droplet generation and control, Sorting and separation, Single-cell analysis, Digital PCR

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic editors

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

Impact

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