Case Report in Molecular Imaging and Nuclear Medicine 2026

This Research Topic marks the inaugural launch of Case Reports in Nuclear Medicine 2026.This new collection highlights high-quality case reports in Nuclear Medicine, encompassing the full clinical spectrum from established diagnostic protocols to the latest frontiers in molecular imaging and targeted therapy. As the field evolves toward more personalized medicine, these reports serve as a vital bridge between clinical practice and academic innovation.

The goal of this Research Topic is to address a persistent gap in accessible, practice-oriented evidence on uncommon and clinically challenging scenarios in Nuclear Medicine. Rapid advances in molecular imaging, hybrid imaging, radiopharmaceutical therapy, and dosimetry create new opportunities but also new diagnostic and management uncertainties. Carefully documented case reports can capture these lessons at the point of care. By bringing together instructive cases, this collection aims to clarify diagnostic pitfalls, tracer or ligand selection, therapeutic decision-making, response assessment, and follow-up, while translating individual observations into practical guidance and hypotheses for future studies.

This Research Topic welcomes only Case Report manuscripts with clear educational value and relevance to Nuclear Medicine; titles should include the phrase "Case Report". We invite submissions on unusual imaging findings, rare diseases, atypical clinical courses, unexpected treatment responses or adverse events, theranostic applications, radioligand therapy, dosimetry, PET/CT, PET/MRI, SPECT/CT, and established or novel radiotracers. Reports should describe the clinical context, imaging or therapy rationale, differential diagnosis, management impact, outcome, and follow-up when available.

We particularly encourage cases that highlight diagnostic pitfalls, support multidisciplinary decisions, or suggest questions for future clinical research.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Data Report
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Clinical Trial
• Data Report
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Policy Brief
• Review
• Study Protocol
• Systematic Review

Keywords: PET, PET/CT, PET/MRI, Radioligand Therapy, SPECT, SPECT/CT, Dosimetry, Imaging, Nuclear Medicine, Medical Imaging

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.