Research Topic

Cancer Dormancy and Metastasis

  • Submission closed.

About this Research Topic

Many patients experience cancer recurrence and metastasis several years or even decades after they have had radical surgery. This phenomenon can be interpreted as cancer dormancy, a period in cancer progression in which residual disease exists, but remains indiscernible or clinically asymptomatic for long ...

Many patients experience cancer recurrence and metastasis several years or even decades after they have had radical surgery. This phenomenon can be interpreted as cancer dormancy, a period in cancer progression in which residual disease exists, but remains indiscernible or clinically asymptomatic for long periods. Tumor dormancy was first defined as early as 1934 by Rupert Willis and then redefined by Geoffrey Hadfield in 1954 as a temporary arrest in mitosis and growth. Thus far, substantial quantities of publications have found three primary potential models that can be put forth to explain the process of dormancy, including angiogenic dormancy, immunologic dormancy, and cellular dormancy. The dynamics of cancer dormancy have been implicated in the recurrence and metastasis of cancer patients.

In this Research Topic, we welcome manuscripts addressing the following themes:

• Pathological issues in, and the definition of, cancer dormancy
• EMT and cancer dormancy
• Cancer stem cells and dormancy
• Environment and cancer dormancy
• Signaling pathways of cancer dormancy
• Models of cancer dormancy
• Clinical management of cancer dormancy


Keywords: EMT, cancer stem cells, dormancy, invasion, metastasis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top
);