About this Research Topic
This Research Topic will serve as the proceedings for the Optogen 2018 workshop and will be open to accepted abstracts submitted to the workshop by 8th February 2019. Abstract submission is available online.
Optical techniques have been one of the key technologies that have enabled significant advances in our understanding of neural circuits within the brain. The ability to control and monitor signalling across populations of neurons is allowing neural circuit dynamics to be studied in unprecedented detail. This capability has been further enhanced now that we can genetically target neurons according to their type. The combination is now allowing the functional connectivity of classes of neurons to be mapped, with the ambition to causally link this to behaviour.
These advances have been made possible through the development of novel molecular tools in tandem with advances in optical technologies. In turn, this is allowing large numbers of neurons to be interrogated simultaneously using light, both as the reporter and as the actuator. A vibrant interdisciplinary research community has now emerged, developing improved fluorescent indicators, optogenetic constructs and sophisticated neural interface technologies. These advances are allowing spatio-temporal monitoring and control of neurons at depth in vivo in the behaving animal.
This Research Topic seeks contributions from neuroscientists, engineers and physicists who are either using these techniques to explore new neuroscience or are developing novel molecular tools, optical technologies or neural interfaces to further research in this area.
Keywords: Optogenics, Neurophotonics, Microscopy, Neuroscience, Imaging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.