Chemical Defenses | List of Frontiers open access articles

Original Research

Published on 10 Nov 2025

Mechanism of hepatotoxicity induced by ethanol extract of Emilia sonchifolia (L.) DC revealed by proteomics and metabolomics

in Predictive Toxicology

Gongzhen Chen
Qiantonghan Luo
Zicong Song
Ping Zheng
Xin Liu
Ting Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669607

482 views

Original Research

Published on 10 Nov 2025

Educators’ perspectives for modernizing dental teaching competencies at Prince Sattam Bin Abdulaziz University-Saudi Arabia: a needs assessment study

in Healthcare Professions Education

Ali Robaian
Nasser Raqe Alqhtani
Abdullah Saad Alqahtani
Abdullah Alshehri
Khaled M. Alzahrani
Tarek Ahmed Soliman

Frontiers in Medicine

doi 10.3389/fmed.2025.1669301

173 views

Original Research

Published on 10 Nov 2025

Cannabidiol potentiates phenobarbital effects in the control of pentylenetetrazole (PTZ)-induced epileptic seizures in neonate rats

in Pediatric Neurology

Lillian Soares Pinto
Matheus Silva de Oliveira
Giovanna Bruno Borges
Olagide Wagner de Castro
Fabrício de Araújo Moreira
Victor Rodrigues Santos

Frontiers in Pediatrics

doi 10.3389/fped.2025.1673345

297 views

Review

Published on 10 Nov 2025

Interaction between gut microbiota and immunity in health and intestinal disease

in Microbial Immunology

Qishang Wang
Qingguo Meng
Yuchao Chen
Yaxin Liu
Xinru Li
Jinjie Zhou
Yuchu Ma
Zihan Yu
Xin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673852

222 views

Original Research

Published on 10 Nov 2025

Unlocking blockchain-driven financial opportunities: optimizing portfolios with cryptocurrencies and European stock markets

in Blockchain Economics

Rebeka Gulyás
Veronika Alexandra Gál
Zoltán Sipiczki

Frontiers in Blockchain

doi 10.3389/fbloc.2025.1665541

462 views

Policy and Practice Reviews

Published on 10 Nov 2025

Global practices in AT provision: considerations for a national assistive technology policy for health in India

in Strengthening Rehabilitation in Health Systems

Rakesh K. Srivastava
Hitesh K. Sharma
Ashoo Grover
Ruchir Malik
Ravinder Singh

Frontiers in Rehabilitation Sciences

doi 10.3389/fresc.2025.1664118

352 views

Systematic Review

Published on 10 Nov 2025

Effects of whole-body vibration training on inflammatory markers and lipid profiles in adults: a systematic review and meta-analysis of randomized controlled trials

in Inflammation

Yan Pan
Ping Luo
Junpeng Pang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705866

252 views

Mini Review

Published on 10 Nov 2025

Integrative regulation of middle cortex formation: from classic modules to emerging pathways

in Plant Development and EvoDevo

Seung Woo Kim
Kwang Suk Chang
Minhee Kang
Jun Lim

Frontiers in Plant Science

doi 10.3389/fpls.2025.1705659

314 views

Review

Published on 10 Nov 2025

Cardiovascular manifestations in mast cell activation disease: key insights for cardiologists and angiologists

in General Cardiovascular Medicine

Wolfgang Taumann
Gerhard J. Molderings

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1705201

708 views

Review

Published on 10 Nov 2025

Harnessing the gut microbiome to modulate ferroptosis: a metabolic strategy for the treatment of digestive tract cancers

in Microbial Immunology

Jiexia Wen
Huagang Liang
Min Zhao
Bin Xuan
Xiangcai Meng
Yang Liu
Liwei Wang
Li He
Tao Zhou
Yang Tao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703964

316 views

Systematic Review

Published on 10 Nov 2025

The potential of acupuncture in treating sarcopenia: a systematic review and meta-analysis of randomized controlled trials

in Aging and Public Health

Xingchen Niu
Dingding Zhang
Tian Gao
Yong Zhang
Dan Zhang
Donghai Li
Ping Zeng

Frontiers in Public Health

doi 10.3389/fpubh.2025.1696030

201 views

Review

Published on 10 Nov 2025

The impact of metabolic reprogramming in hepatocellular carcinoma on T cell

in Cancer Immunity and Immunotherapy

Dong-Xu Liao
Xiang An
Gui-Xiang Huang
Tong-Ling Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696113

233 views

Systematic Review

Published on 10 Nov 2025

Acromegaly and breast cancer risk: evidence from a systematic review and meta-analysis

in Cancer Endocrinology

Hee Christy Lee
Shruti N. Shah
John Koo
Caitlin Plovnick
Nidhi Agrawal

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1696291

311 views

Original Research

Published on 10 Nov 2025

The correlation between the use of ondansetron and mortality in sepsis associated encephalopathy patients: a retrospective ICU cohort study

in Pharmacoepidemiology

Shuo Yang
Yi-Qu Wei
Ya-Zhou Liu
Xiao-Lin Wang
Jin-Xia Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712328

419 views

Review

Published on 10 Nov 2025

Advancing precision medicine in axial spondyloarthritis: insights from multi-omics approaches

in Precision Medicine

Yuanpiao Ni
Quanbo Zhang
Xin Wu
Huji Xu
Yufeng Qing

Frontiers in Medicine

doi 10.3389/fmed.2025.1715420

305 views

Clinical Trial

Published on 10 Nov 2025

Pharmacokinetics, mass balance, and metabolism of the novel potassium-competitive acid blocker JP-1366 in healthy Chinese adults following a single oral dose of [14C]JP-1366

in Drug Metabolism and Transport

Xuemei Liu
Decheng Deng
Jian Meng
Haitang Hu
Quankun Zhuang
Xue Zhou
Long Fu
Binke Fan
Xueting Xu
Qin Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701581

236 views

Articles

Mechanism of hepatotoxicity induced by ethanol extract of Emilia sonchifolia (L.) DC revealed by proteomics and metabolomics

Educators’ perspectives for modernizing dental teaching competencies at Prince Sattam Bin Abdulaziz University-Saudi Arabia: a needs assessment study

Cannabidiol potentiates phenobarbital effects in the control of pentylenetetrazole (PTZ)-induced epileptic seizures in neonate rats

Interaction between gut microbiota and immunity in health and intestinal disease

Unlocking blockchain-driven financial opportunities: optimizing portfolios with cryptocurrencies and European stock markets

Global practices in AT provision: considerations for a national assistive technology policy for health in India

Effects of whole-body vibration training on inflammatory markers and lipid profiles in adults: a systematic review and meta-analysis of randomized controlled trials

Integrative regulation of middle cortex formation: from classic modules to emerging pathways

Cardiovascular manifestations in mast cell activation disease: key insights for cardiologists and angiologists

Harnessing the gut microbiome to modulate ferroptosis: a metabolic strategy for the treatment of digestive tract cancers

The potential of acupuncture in treating sarcopenia: a systematic review and meta-analysis of randomized controlled trials

The impact of metabolic reprogramming in hepatocellular carcinoma on T cell

Acromegaly and breast cancer risk: evidence from a systematic review and meta-analysis

The correlation between the use of ondansetron and mortality in sepsis associated encephalopathy patients: a retrospective ICU cohort study

Advancing precision medicine in axial spondyloarthritis: insights from multi-omics approaches

Pharmacokinetics, mass balance, and metabolism of the novel potassium-competitive acid blocker JP-1366 in healthy Chinese adults following a single oral dose of [14C]JP-1366