Frontal Areas | List of Frontiers open access articles

Original Research

Published on 26 Nov 2025

Machine learning-based prediction of response to Janus kinase inhibitors in patients with rheumatoid arthritis using clinical data

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yeo-Jin Lee
Gyucheol Choi
Joongyeub Yeo
Jiyeong Baek
Heeju Choi
Minji Kim
Yong-Gil Kim
Bo Young Kim
Jamin Koo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689144

233 views

Original Research

Published on 26 Nov 2025

Dynamic functional connectivity of the amygdala-hippocampal complex is associated with cognitive impairment in adolescents with Internet gaming disorder

in Addictive Disorders

Tao Zhao
Shuyi Zhang
Qiyan Lv
Yange Li
Dingyi Li
Meijun Liu
Yan Lang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1689119

249 views

Editorial

Published on 26 Nov 2025

Editorial: Foundation models for healthcare: innovations in generative AI, computer vision, language models, and multimodal systems

in Computer Vision

Sokratis Makrogiannis

Frontiers in Computer Science

doi 10.3389/fcomp.2025.1744581

294 views

Correction

Published on 26 Nov 2025

Correction: Construction of a risk prediction model for postoperative atrial ﬁbrillation in lung cancer patients based on multidimensional feature fusion and ensemble learning

in General Cardiovascular Medicine

Ziwei Gong
Silamuguli Haierla
Jing Shi
Xinya Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1743452

203 views

Brief Research Report

Published on 26 Nov 2025

Exploratory spatial transcriptomic profiling of peritumoral Th2 immune polarization in HPV-positive oropharyngeal cancer

in Cancer Immunity and Immunotherapy

Naohiro Wakisaka
Makiko Moriyama-Kita
Satoru Kondo
Eiji Kobayashi
Takayoshi Ueno
Yosuke Nakanishi
Kazuhira Endo
Hisashi Sugimoto
Tomokazu Yoshizaki

Frontiers in Oncology

doi 10.3389/fonc.2025.1732480

444 views

Original Research

Published on 26 Nov 2025

Spatial networks of China's specialized, refined, distinctive, and innovative medical device firms based on parent–subsidiary contacts: implications for regional health policy

in Public Health Policy

Feng Hu
Huijie Yang
Shaobin Wei
Hao Hu
Yufeng Chen
Haiyan Zhou

Frontiers in Public Health

doi 10.3389/fpubh.2025.1676189

339 views

Original Research

Published on 26 Nov 2025

Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning

in Respiratory Pharmacology

Kai Xie
Xiajin Huang
Zhen Li
Wenjing Yin
Xiaoxuan He
Xinyu Miao
Haifeng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660893

314 views

Original Research

Published on 26 Nov 2025

Myosteatosis as an independent predictor for all-cause and cardiac mortality in initial-dialysis patients: a multicenter, retrospective cohort study

in Renal Physiology and Pathophysiology

Shi-Mei Hou
Min Li
Jing-Yuan Cao
Yao Wang
Min Yang
Li Tian
Yan-Hong Ni
Bi-Xia Yang
Li-Rong Hao
Jian-Bing Hao

Frontiers in Physiology

doi 10.3389/fphys.2025.1687179

221 views

Original Research

Published on 26 Nov 2025

Sustainable management of simulated coffee processing wastewater using micro-aeration enhanced anaerobic digestion: a long-term technical evaluation

in Waste Management

Kayode J. Taiwo
Samuel O. Ogundipe
William L. Kerr
Ronald B. Pegg
Joon Hyuk Suh
Joseph G. Usack

Frontiers in Sustainability

doi 10.3389/frsus.2025.1681014

271 views

Original Research

Published on 26 Nov 2025

Development of a nucleocapsid protein-based competitive ELISA for the detection of porcine deltacoronavirus antibodies

in Infectious Agents and Disease

Shuizhong Han
Yu Zhou
Maiping Li
Penggang Chen
Xingming Huang
Ying Wang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1680835

661 views

Original Research

Published on 26 Nov 2025

Coupling coordination evaluation and influencing factors analysis of older adult care service resource supply and demand in China

in Health Economics

Lingxiao Guo
Hua Wei
Qunshan Tao
Kunyu Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1662064

165 views

Original Research

Published on 26 Nov 2025

Drug repurposing for Chagas disease: overcoming the hit-to-preclinical candidate stage

in Molecular Sciences

Claudia Veira
Belén Dávila
Elva Serna
Nilda Portillo
Gloria Yaluff
Guzmán Álvarez
Hugo Cerecetto
Elena Aguilera

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1662907

241 views

Original Research

Published on 26 Nov 2025

Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression

in Cancer Immunity and Immunotherapy

Wenjia Ge
Ziwei Zhang
Wenjie Chen
Zhijie Zhao
Huabao Cai
Yantao Ding
Jin Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662869

223 views

Review

Published on 26 Nov 2025

Smart classrooms, unheard perspectives: a global review of technology integration and local challenges in deaf and hard-of-hearing education in Saudi Arabia

in Special Educational Needs

Fatimah Abdullah Almulhim

Frontiers in Education

doi 10.3389/feduc.2025.1663912

369 views

Original Research

Published on 26 Nov 2025

Immune checkpoint inhibitor therapy in advanced cancer: clinical association of irAEs type, inflammatory markers and efficacy

in Cancer Immunity and Immunotherapy

Mengying Qian
Ping Ma
Yu Zhao
Hao Jiang
LiYang Gao
Gaoyang Lin
Difan Duan
Jinmin Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662333

216 views

Review

Published on 26 Nov 2025

MIS-C pathogenesis: immune dysregulation & viral triggers

in Viral Immunology

Tiantian Xu
Jiamin Zhang
Xiangyuan Hou
Xinyu Xie
Junye Qi
Changbing Wang
Yuqing Yan
Lu Kuang
Bing Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624963

397 views

Articles

Machine learning-based prediction of response to Janus kinase inhibitors in patients with rheumatoid arthritis using clinical data

Dynamic functional connectivity of the amygdala-hippocampal complex is associated with cognitive impairment in adolescents with Internet gaming disorder

Editorial: Foundation models for healthcare: innovations in generative AI, computer vision, language models, and multimodal systems

Correction: Construction of a risk prediction model for postoperative atrial ﬁbrillation in lung cancer patients based on multidimensional feature fusion and ensemble learning

Exploratory spatial transcriptomic profiling of peritumoral Th2 immune polarization in HPV-positive oropharyngeal cancer

Spatial networks of China's specialized, refined, distinctive, and innovative medical device firms based on parent–subsidiary contacts: implications for regional health policy

Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning

Myosteatosis as an independent predictor for all-cause and cardiac mortality in initial-dialysis patients: a multicenter, retrospective cohort study

Sustainable management of simulated coffee processing wastewater using micro-aeration enhanced anaerobic digestion: a long-term technical evaluation

Development of a nucleocapsid protein-based competitive ELISA for the detection of porcine deltacoronavirus antibodies

Coupling coordination evaluation and influencing factors analysis of older adult care service resource supply and demand in China

Drug repurposing for Chagas disease: overcoming the hit-to-preclinical candidate stage

Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression

Smart classrooms, unheard perspectives: a global review of technology integration and local challenges in deaf and hard-of-hearing education in Saudi Arabia

Immune checkpoint inhibitor therapy in advanced cancer: clinical association of irAEs type, inflammatory markers and efficacy

MIS-C pathogenesis: immune dysregulation & viral triggers