Hard Problems | List of Frontiers open access articles

Original Research

Published on 03 Mar 2026

Spatial configuration and sustainability: decoding the landscape genes of traditional Li settlements in Hainan Island through a production-living-ecological space framework

in Land Use Dynamics

Yizhe Yuan
Dinghai Yang
Rui Zhang
Zhijian Chen
Yuan Meng

Frontiers in Environmental Science

doi 10.3389/fenvs.2026.1755099

Original Research

Published on 03 Mar 2026

Networked evolutionary game analysis of low-carbon technology diffusion

in Social Physics

Xiaoxiao Sun
Jianguo Du
Xiaowen Zhu

Frontiers in Physics

doi 10.3389/fphy.2026.1753750

150 views

Original Research

Published on 03 Mar 2026

Production of safe beef in Uganda: who are the most influential actors and what are the challenges?

in Product Quality Archive

Patrick Okello
John Ilukor
Kanifa Kamatara
Nelson Turyahabwe

Frontiers in Animal Science

doi 10.3389/fanim.2025.1672528

373 views

Systematic Review

Published on 03 Mar 2026

The impact of bright light therapy on non-motor symptoms in patients with Parkinson’s disease: a systematic review and meta-analysis

in Dementia and Neurodegenerative Diseases

Junjie Geng
Han li Yu
Liping Tan

Frontiers in Neurology

doi 10.3389/fneur.2026.1770673

130 views

Perspective

Published on 03 Mar 2026

Equity at the point of care: auditing AI-supported resource allocation in obstetric emergencies

in Digital Public Health

Fan Gao
Danli Xie

Frontiers in Public Health

doi 10.3389/fpubh.2026.1774367

603 views

Original Research

Published on 03 Mar 2026

Bioequivalence study of testosterone undecanoate soft capsules in healthy postmenopausal women under fed conditions: a single-center, four-period, repeated crossover trial

in Drug Metabolism and Transport

Nanxing Li
Fengjia Zhu
Zhongyuan Zhao
Shilong Zhu
Jinlian Wu
Xu Zuo
Jinjin Shi
Xiuhui Qian
Xiaoping Zhang
Yuanyuan Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1763835

Original Research

Published on 03 Mar 2026

Mining the candidate transcription factors modulating dendrobine biosynthesis under phosphate deficiency in Dendrobium officinale Kimura & Migo

in Plant Metabolism and Chemodiversity

Siqi Gui
Jiening Wu
Yifei Shi
Chao Zhuang
Junjie Zhong
Xiaowei Zou
Hui Du
Wei Zhou

Frontiers in Plant Science

doi 10.3389/fpls.2026.1784768

108 views

Original Research

Published on 03 Mar 2026

School attendance matters: co-occurring trajectories of school attendance and academic achievement from elementary to secondary school in a Canadian context

in Child Mental Health and Interventions

Heather Brittain
Tracy Vaillancourt

Frontiers in Child and Adolescent Psychiatry

doi 10.3389/frcha.2026.1729744

252 views

Original Research

Published on 03 Mar 2026

Unraveling the volatile profile and bioactivity of Zhoupigan (Citrus reticulata cv. Manau Gan) essential oil via HS-GC-IMS and HS-SPME-GC-MS: a comprehensive evaluation of different extraction techniques

in Food Chemistry

Huanhuan Xu
Jialiang Zou
Xuelian Gan
Fu Wang
Lin Chen
Hongping Chen
Yuan Hu
Youping Liu

Frontiers in Nutrition

doi 10.3389/fnut.2026.1775469

166 views

Original Research

Published on 03 Mar 2026

Supervisor–group culture, age and the stress–burnout mechanism: a qualitative study of Chinese doctoral students

in Educational Psychology

Shuman Xie
Siliang Yu
Lijun Xu

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1794711

Case Report

Published on 03 Mar 2026

Case Report: Sufficient pelvic floor muscle function can retain acceptable postoperative defecation function after in-situ anal reconstruction surgery in patients with ultra-low rectal/anal cancer

in Surgical Oncology

Li Lin
Yihui Lei
Guoyan Liu

Frontiers in Surgery

doi 10.3389/fsurg.2026.1762110

104 views

Original Research

Published on 03 Mar 2026

Electroacupuncture-augmented breaststroke vs. breaststroke alone for mild AIS: superior correction in a retrospective cohort

in Pediatric Orthopedics

Xiao Ma
Yuanyuan Zhang
Shilin Lian
Zhuyun Cai
Weihong Li
Tianwen Ye
Rui Gao

Frontiers in Pediatrics

doi 10.3389/fped.2026.1720305

225 views

Review

Published on 03 Mar 2026

Models of cartilage repair with autologous mesenchymal stem cells seeded on scaffolds: a systematic narrative review

in Biomaterials

Mikołaj Wróbel
Hubert Rytel
Igor Jaszczyszyn
Maciej Maj
Jacek Malejczyk
Izabela Róża Janiuk

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1762579

185 views

Original Research

Published on 03 Mar 2026

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

in Cytokines and Soluble Mediators in Immunity

Melanie Ohm
Wei He
Dunja Bruder
Karsten Hiller
Martin Korte
Shirin Hosseini

Frontiers in Immunology

doi 10.3389/fimmu.2026.1776302

102 views

Original Research

Published on 03 Mar 2026

Influencing factors of physical exercise motivation among military academy cadets: a social ecological model analysis

in Mental Health Occupational Therapy

Wenqi Wang
Chao Xu
Guoxian Gao
Cheng Zhang
Fengxiang Wang
Yanliang Song
Wei Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1741195

101 views

Original Research

Published on 03 Mar 2026

Toward a visualized classifier for depression: characterization of hemodynamic patterns using time-domain fNIRS

in Neuroimaging

Cyrus Su Hui Ho
Shujun Jing
Zhifei Li
Gabrielle Wann Nii Tay
Rachael Rui Qi Loh
Kenneth De Sheng Tong
Jinyuan Wang
Junyi Li
E Du
Nanguang Chen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1724011

Articles

Spatial configuration and sustainability: decoding the landscape genes of traditional Li settlements in Hainan Island through a production-living-ecological space framework

Networked evolutionary game analysis of low-carbon technology diffusion

Production of safe beef in Uganda: who are the most influential actors and what are the challenges?

The impact of bright light therapy on non-motor symptoms in patients with Parkinson’s disease: a systematic review and meta-analysis

Equity at the point of care: auditing AI-supported resource allocation in obstetric emergencies

Bioequivalence study of testosterone undecanoate soft capsules in healthy postmenopausal women under fed conditions: a single-center, four-period, repeated crossover trial

Mining the candidate transcription factors modulating dendrobine biosynthesis under phosphate deficiency in Dendrobium officinale Kimura & Migo

School attendance matters: co-occurring trajectories of school attendance and academic achievement from elementary to secondary school in a Canadian context

Unraveling the volatile profile and bioactivity of Zhoupigan (Citrus reticulata cv. Manau Gan) essential oil via HS-GC-IMS and HS-SPME-GC-MS: a comprehensive evaluation of different extraction techniques

Supervisor–group culture, age and the stress–burnout mechanism: a qualitative study of Chinese doctoral students

Case Report: Sufficient pelvic floor muscle function can retain acceptable postoperative defecation function after in-situ anal reconstruction surgery in patients with ultra-low rectal/anal cancer

Electroacupuncture-augmented breaststroke vs. breaststroke alone for mild AIS: superior correction in a retrospective cohort

Models of cartilage repair with autologous mesenchymal stem cells seeded on scaffolds: a systematic narrative review

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

Influencing factors of physical exercise motivation among military academy cadets: a social ecological model analysis

Toward a visualized classifier for depression: characterization of hemodynamic patterns using time-domain fNIRS