Hit Compounds Optimization | List of Frontiers open access articles

Community Case Study

Published on 02 Mar 2026

Implementation of an innovative virtual selective screening program for early detection of cerebral palsy in British Columbia

in Public Health Policy

Keith O'Connor
Nandy Fajardo
Carol Lai
Vivian Wong
Mor Cohen-Eilig
Ram A. Mishaal

Frontiers in Public Health

doi 10.3389/fpubh.2026.1754120

421 views

Original Research

Published on 02 Mar 2026

Identification of preschool children's physical fitness phenotypes and their association with multidimensional body shape indicators: a data-driven approach with risk prediction modeling

in Children and Health

Xiaoxiao Chen
Deqiang Zhao
Aoyu Zhang
Xiang Pan
Chuanmiao Wang
Jiaxin Chen
Yanfeng Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2026.1773424

100 views

Original Research

Published on 02 Mar 2026

Host biological sex directs immune control of the Plasmodium parasite liver stage in mice

in Parasite Immunology

Caroline J. Duncombe
Alen S. Poehlman
Ethan N. Conrad
Nilasha Sen
Aaron Ayenew
Rebecca C. Blyn
GW McElfresh
Elizabeth K. K. Glennon
Kenneth Boey
Anya C. Kalata

Frontiers in Immunology

doi 10.3389/fimmu.2026.1734587

194 views

Perspective

Published on 02 Mar 2026

Scaling injustice: epistemic harm in DID and what clinical records will teach AI

in Psychopathology

Oluwafunmilayo Akinlade

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1741240

Original Research

Published on 02 Mar 2026

Genomic and functional characterization of a lytic Klebsiella phage UHKP with antibiofilm activity

in Phage Biology

Muhammad Hassan
Iqbal Ahmad Alvi
Sadiq Noor Khan
Dawood Ahmed
Muhammad Asif
Afshan Saleem

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1775638

335 views

Original Research

Published on 02 Mar 2026

Protective antigens hidden in the bovine Clostridium vaccine

in Microbial Immunology

He Qin
Jiahui Xie
Qiuyan Deng
Jingjing Ren
Lihe Su
Weiye Zuo
Yue Lv
Haojie Dong
Zhaoquan Liu
Xun Ma

Frontiers in Immunology

doi 10.3389/fimmu.2026.1751922

Original Research

Published on 02 Mar 2026

Refining the employability of university students from low-income families: a qualitative study on the influential factors and mechanism of employability

in Educational Psychology

Dan Wang
Bohan Liu
Yujie Duan
Yue Liang
Di Wu
Dan Zhang
Chao Song

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1718245

168 views

Original Research

Published on 02 Mar 2026

Lipid metabolism dysregulation in solar lentigo: a multi-system-level analysis reveals membrane instability and energy homeostasis disruption

in Molecular and Cellular Pathology

Sohyun Kim
Wonmin Lee
Junghyun Kim
Yoonsung Lee
Kiwon Lee
Man S. Kim
Soon-Hyo Kwon

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1751543

Original Research

Published on 02 Mar 2026

Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species

in Pharmacology of Infectious Diseases

Islam Ahaik
Juan Carlos Nunez-Rodriguez
Sònia Abelló-Cros
Oscar Yanes
Samira Bouhdid
Toni Gabaldón

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1756267

253 views

Systematic Review

Published on 02 Mar 2026

Hemiarthroplasty vs. proximal femoral nail fixation in unstable pertrochanteric fractures: an updated systematic review and meta-analysis

in Orthopedic Surgery

Ming-Ming Zhang
Shuang-Shuang Yuan
Hong-Hua Dong
Chao Wang

Frontiers in Surgery

doi 10.3389/fsurg.2026.1782908

108 views

Methods

Published on 02 Mar 2026

Development of a point-of-care dual one-step recombinase-aided PCR assay for rapid identification of Mycobacterium tuberculosis gyrA mutations conferring fluoroquinolone resistance

in Antimicrobials, Resistance and Chemotherapy

Xingyu Liu
Kenan Peng
Yuanrui Li
Shihao Jiao
Jianing Wu
Duoxiao Zhang
Shijue Gao
Yujie Xiang
Junkai Ren
Qian Ma

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1772984

Original Research

Published on 02 Mar 2026

Dynamic changes and prognostic utility of procalcitonin, D-dimer, and lactate dehydrogenase in patients with sepsis and septic shock

in Intensive Care Medicine and Anesthesiology

Qiuxia Ge
Weijuan Song
Hongmei Ding
Haojie Wu
Zhen Ren

Frontiers in Medicine

doi 10.3389/fmed.2026.1771448

Study Protocol

Published on 02 Mar 2026

Cohort profile: the Resilient Minds national study of mental health and cognitive resilience in community dwelling adults aged 18 to 93

in Health Technology Implementation

Kaarin J. Anstey
Brooke Brady
Lidan Zheng
Jana Koch
Md Hamidul Huque
Michelle K. Lupton
Ralph Martins
Daniel Ashworth
Erin Goddard
Nikki-Anne Wilson

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1710349

344 views

Original Research

Published on 02 Mar 2026

Neural correlates in the time course of inferences: costs and benefits for less-skilled readers at the university level

in Cognitive Science

Mabel Urrutia
Esteban J. Pino
María Troncoso-Seguel
Claudio Bustos
Pamela Guevara
Karina Torres-Ocampo
Sandra Mariángel
Yang Fu
Hipólito Marrero

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1692021

Original Research

Published on 02 Mar 2026

TEGA toolkit: a validated framework for inclusive analog game design in higher education

in Language, Culture and Diversity

Sara Rye

Frontiers in Education

doi 10.3389/feduc.2025.1670301

612 views

Original Research

Published on 02 Mar 2026

Antimicrobial mechanism of Phyllanthus niruri L. against oral pathogens: a scanning and transmission electron microscopy study

in Pediatric Dentistry

Vanishree H. Shivakumar
Anand S. Tegginamani
Raghavendra M. Shetty
Annapurny Venkiteswaran
Nurhayati Mohamad Zain
Nurul ‘Izzah Mohd Sarmin
Zolkapli Eshak
Eddy Hasrul Hassan

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1696836

120 views

Articles

Implementation of an innovative virtual selective screening program for early detection of cerebral palsy in British Columbia

Identification of preschool children's physical fitness phenotypes and their association with multidimensional body shape indicators: a data-driven approach with risk prediction modeling

Host biological sex directs immune control of the Plasmodium parasite liver stage in mice

Scaling injustice: epistemic harm in DID and what clinical records will teach AI

Genomic and functional characterization of a lytic Klebsiella phage UHKP with antibiofilm activity

Protective antigens hidden in the bovine Clostridium vaccine

Refining the employability of university students from low-income families: a qualitative study on the influential factors and mechanism of employability

Lipid metabolism dysregulation in solar lentigo: a multi-system-level analysis reveals membrane instability and energy homeostasis disruption

Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species

Hemiarthroplasty vs. proximal femoral nail fixation in unstable pertrochanteric fractures: an updated systematic review and meta-analysis

Development of a point-of-care dual one-step recombinase-aided PCR assay for rapid identification of Mycobacterium tuberculosis gyrA mutations conferring fluoroquinolone resistance

Dynamic changes and prognostic utility of procalcitonin, D-dimer, and lactate dehydrogenase in patients with sepsis and septic shock

Cohort profile: the Resilient Minds national study of mental health and cognitive resilience in community dwelling adults aged 18 to 93

Neural correlates in the time course of inferences: costs and benefits for less-skilled readers at the university level

TEGA toolkit: a validated framework for inclusive analog game design in higher education

Antimicrobial mechanism of Phyllanthus niruri L. against oral pathogens: a scanning and transmission electron microscopy study