The following Research Topics are led by experts in their field and contribute to the scientific understanding of oncology. These Research topics are published in the peer-reviewed journal Frontiers in Oncology, as open access articles.
Research Topic
Molecular Mechanisms and Targeted Therapies for Colorectal Cancer Vol II
Background: Colorectal cancer (CRC) stands as a global health challenge, ranking as the third most prevalent cancer and claiming over 500,000 lives annually.
Research Topic
Biomarker-Guided Strategies in NSCLC Immunotherapy
The goal of this research topic is to explore different biomarker-guided strategies for effective patient selection, treatment de-escalation, and immunotherapy-based treatment combinations.
Research Topic
Enhancing AI Model Interpretation in Radiation Oncology Through Uncertainty Quantification
This Research Topic aims to promote research in AI uncertainty quantification and application as a high impact research field, with a mixture of both academic and clinical interest.
Research Topic
Multidisciplinary Management of Skull-Base Tumours
This research topic is designed to provide a platform for researchers, clinicians, and experts from various disciplines to share their insights and contribute to the evolving landscape of skull-base cancer management.
Research Topic
Recent Biological Insights into Pediatric Brain Tumors
This Research Topic will focus on many of the most critical areas pertinent to childhood central nervous system malignancy that have recently assumed prominence in the care of children and young adults with brain cancer.
Research Topic
Challenges and Strategies in the Management of ER/PgR Low-Expression Breast Cancer: Exploring Fundamentals, Clinical Insights, and Treatment Approaches
This research topic aims to delve into the complexities of hormone receptor-low expression breast cancer, an emerging and significant subtype.
Research Topic
Crosstalk between Lung Cancer and Fibrosis: Pathogenesis and Therapeutic Strategies
Background: Lung cancer is one of the primary causes of cancer-related mortality globally, with its microenvironment playing a crucial role in tumor progression and the development of therapeutic resistance.
Research Topic
Overcoming Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma
This research topic aims to explore the molecular mechanisms associated with therapeutic resistance in HNSCC and develop novel therapeutic strategies to overcome this resistance.
Research Topic
Technology Developments in Proton Therapy
Background: Proton therapy is a radiation cancer therapy modality that aims to irradiate tumors with submillimeter precision.
Research Topic
Insights, Controversies, and New Developments in the Initial Treatment Decisions for Advanced Epithelial Ovarian Cancer
In this Research Topic, we aim to consolidate insightful perspectives on the initial treatment of advanced epithelial ovarian cancer, discuss the controversies, and explore new developments in hopes of improving the prognosis.
Research Topic
The Immunosuppressive Microenvironment in Pediatric Cancers: Applications and Considerations in Immunotherapy
The overarching goal of this research topic is to enhance the efficacy of immunotherapy in pediatric cancers by deciphering and modulating the immunosuppressive microenvironment.
Research Topic
The Role of HPV In GU Oncology
The Research Topic will accept research dealing with the potential causal role of HPV in GU cancers not usually associated with this virus.
Research Topic
Host Features Affecting CAR T Cell Therapy of Hematological Malignancies
The Research Topic focuses on host-intrinsic features that can modulate the therapeutic response to CAR T-cells.
Research Topic
Liquid Biopsy and Circulating Tumor DNA Assays in the Management of Breast Cancer
Since the discovery of cell-free DNA (cfDNA) in 1948, shedded DNA fragments have been applied to technologies ranging from pre-natal genetic screening and diagnosis, genomic medicine, cancer susceptibility and tumor dynamics assessments.
Research Topic
Immunological Therapies in Pediatric Cancers: A Latin American Perspective
This research topic aims to foster international collaboration across Latin America to enhance understanding of the use of various immunological therapies in pediatric cancers, including leukemia, lymphomas, and solid tumors.
Research Topic
BCL-2 Family Inhibitors in Hematologic Malignancies
The main objective of this Research Topic is to encourage research papers that investigate these questions and bring novel and impactful knowledge for more effective clinical treatments utilizing BCL-2 inhibitors.
Research Topic
150 Years of Laryngectomy: Reviews on the State of the Art and Future Perspectives
This Research Topic will sum up the main content of this symposium addressing the current issues around surgical and non-surgical treatment of laryngeal cancer.
Research Topic
Organ Preservation in Rectal Cancer
The goal of this Research Topic is to discuss the potential strategies for organ preservation in patients with rectal cancer.