About this Research Topic
The overall goals of this Research Topic are to further understand the molecular and cellular responses of injured neural cells (neurons and glia) and to develop highly effective strategies for repairing lesioned CNS and restoring neurological functions.
We invite investigators to contribute original research or review articles that highlight recent achievements in the molecular and cellular mechanisms underlying neural damages, regeneration failure, and functional loss; as well as in developing various strategies to enhance CNS repair, cell survival, axon regeneration, re-myelination, and functional recovery. Potential topics include, but not limited to, the following:
• Understanding the molecular and cellular responses of neural cells to CNS injuries or in neurological disorders;
• Understanding the novel mechanisms underlying cell loss/damage and regeneration failure in the lesioned CNS;
• Advances in elucidating signalling pathways and cellular targets in mediating CNS cell growth, regeneration, and neuroplasticity;
• Developing therapeutic strategies promoting cell survival, axon regeneration, re-myelination, and functional recovery by targeting extrinsic, intrinsic, and other factors.
Keywords: CNS injury, neural repair, axon regeneration, therapeutic strategies, neuroplasticity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.