About this Research Topic
Polygenic risk scores (PRS) have gained prominence as a genetic tool with the promise to revolutionize medicine and improve biomedical outcomes at the level of individuals. However, the clinical utility of PRS will certainly vary between diseases and populations of different ancestries. To realize the full and equitable potential of PRS, we are calling for papers that evaluate PRS for traits and diseases in diverse populations and also works that address potential ethical and scientific challenges surrounding the clinical implementation of PRS.
Keywords: genetic risk scores, single nucleotide polymorphism, SNP, genome-wide association, association
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.