About this Research Topic
Regenerative medicine and surgery is the new frontier in ophthalmology. The cornea offers unique characteristics and a privileged scenarium to develop these techniques. Recently published basic research and translational research indicates that either the ocular surface, particularly the corneal epithelium, the corneal stroma and endothelium can be regenerated without the need for allogenic grafts. There is at this moment solid clinical evidence of this progress and the future perspective on the topic is immense. Advanced therapies based on the use of different types of stem cells have been progressing and are at this moment becoming available in some countries. The purpose of this review is to offer the practical ophthalmologist a real perspective based on evidence about what corneal regeneration therapy may offer today to the practicing clinician and the corneal surgeon.
This Research Topic will be focused on review papers that will be based on the analysis of the evidence existing about the different techniques that have been proposed on a clinical human basis for the regeneration of the corneal epithelium and the ocular surface, the corneal stroma, and the corneal endothelium and its practical applications.
Topic editor Dr. Sophie Deng is employed by Dompe US and Kowa Research Institute, Inc. Dr. Sophie Deng also received grant support from the National Eye Institute and the California Institute for Regenerative Medicine. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords: Cornea, regenerative medicine, corneal transplantation, corneal stromal expansion, stem cells, corneal endothelial regeneration, ocular surface regeneration
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.