About this Research Topic
With a surge of antibody-associated CNS disorders, clinicians are faced with emerging challenges, including (1) the clinical significance and diagnostic value of antibodies; (2) the diagnostic dilemma in circumstances of "coexisting antibodies" or “negative antibody"; (3) the standardization of antibody detection assay; (4) lack of robust evidence endorsing treatment strategies for antibody-associated CNS autoimmune diseases. All these issues are worthy of exploration in depth.
This Research Topic aims to provide novel scientific data and gain further understanding of clinical presentation, neuroimaging, antibody analysis and other relevant investigations of antibody-mediated autoimmune diseases of the CNS. Moreover, we want to highlight recent advances in diagnostic approaches and therapeutic regimens in this expanding spectrum of diseases. Both Original Research and Review articles will be considered for submission. In addition, a variety of other publications, including editorials, commentaries and perspectives, case reports and other works are also welcome if relevant insights to the field are provided.
We would like to acknowledge that Dr. Yinxi Zhang, Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, has acted as a coordinator and has contributed to the preparation of the proposal for this Research Topic.
Keywords: Antibody; Autoimmune diseases; Central nervous system; Neuroimmunology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.