Research Topic

The Role of Exosomes in Metabolic and Endocrine Disease

About this Research Topic

Exosomes act as biological mediators in different physiological and biological functions through cell-to-cell communication, such as participating in immunosuppression, facilitating antigen presentation, and signal transfer. Exosomes play a pivotal role in a wide spectrum of diseases such as tumorigenesis, cardiovascular disease, nephropathy, metabolic disease and so on. Although the functions of exosomes are largely unknown, progress has been made in recent years revealing the role of exosomes in the physiological and pathological function of cancer, cardiovascular disease, metabolic disease, kidney disease, and others. Moreover, exosomes in serum are also proposed to be a biomarker for some diseases.

This Research Topic aims to delineate the functionalities of exosomes in their physiological and pathological roles in different metabolic and endocrine diseases. It will cover a spectrum of research interests that draw a holistic view to reveal the function and mechanisms of exosomes in diagnosis, prognosis, and therapeutics.
Original research and reviews covering novel studies of exosomes in their physiological and pathological roles in metabolic and endocrine disease, such as diabetes mellitus, thyroid disease, adrenal disease, etc. are welcome.

Potential topics include, but are not limited to:
• Novel treatments/targets of exosomes for metabolic and endocrine disease.
• Basic and preclinical studies that help reveal the pathology underlying metabolic and endocrine disease.
• Exosomes as novel biomarkers in identifying metabolic and endocrine disease.


Keywords: Exosomes, metabolic disease, endocrine disease, biomarker, pathophysiologic mechanism


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Exosomes act as biological mediators in different physiological and biological functions through cell-to-cell communication, such as participating in immunosuppression, facilitating antigen presentation, and signal transfer. Exosomes play a pivotal role in a wide spectrum of diseases such as tumorigenesis, cardiovascular disease, nephropathy, metabolic disease and so on. Although the functions of exosomes are largely unknown, progress has been made in recent years revealing the role of exosomes in the physiological and pathological function of cancer, cardiovascular disease, metabolic disease, kidney disease, and others. Moreover, exosomes in serum are also proposed to be a biomarker for some diseases.

This Research Topic aims to delineate the functionalities of exosomes in their physiological and pathological roles in different metabolic and endocrine diseases. It will cover a spectrum of research interests that draw a holistic view to reveal the function and mechanisms of exosomes in diagnosis, prognosis, and therapeutics.
Original research and reviews covering novel studies of exosomes in their physiological and pathological roles in metabolic and endocrine disease, such as diabetes mellitus, thyroid disease, adrenal disease, etc. are welcome.

Potential topics include, but are not limited to:
• Novel treatments/targets of exosomes for metabolic and endocrine disease.
• Basic and preclinical studies that help reveal the pathology underlying metabolic and endocrine disease.
• Exosomes as novel biomarkers in identifying metabolic and endocrine disease.


Keywords: Exosomes, metabolic disease, endocrine disease, biomarker, pathophysiologic mechanism


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

30 November 2020 Abstract
17 March 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

30 November 2020 Abstract
17 March 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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