Research Topic

EXPOSOME: the cutting edge knowledge in the exposure science

About this Research Topic

This Research Topic will bring together manuscripts dealing with different exposures in the same epidemiological design leading to the emergence of the exposome concept. This term was coined by Wild in 2005 and comprises of the totality of human exposures throughout life, from conception to death. The exposome is concomitantly based on three domains: i) Internal factors that are unique to individuals, such as physiology, age, body morphology, and an individual’s genome; ii) General external factors, which includes socioeconomic condition, sociodemographic factors, and place of residence; and iii) Specific external factors, such as diet, lifestyle, environmental and occupational exposures, among others.

We welcome manuscripts on:

(i) Exposome-related approaches such as systems biology, high-performance toxicological screening, temporal and spatial statistical models;

(ii) Translation of the importance of environmental factors in diseases using principles of exposome;

(iii) New scientific findings to boost and improve sustainability, prevention, or treatment strategies in humans;

(iv) Characterizing of the internal exposome at the individual level by integrating data – omics (transcriptomics, proteomics, metabolomics, microbiomics) and monitoring;

(v) Scientific guidance on risk assessment based on exposome;

(vi) Understanding how general and specific external factors influence the risk of chronic diseases.


Keywords: exposome, proteomics, metabolomics, microbiomics, transcriptomics, environmental factors, toxicological screening


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

This Research Topic will bring together manuscripts dealing with different exposures in the same epidemiological design leading to the emergence of the exposome concept. This term was coined by Wild in 2005 and comprises of the totality of human exposures throughout life, from conception to death. The exposome is concomitantly based on three domains: i) Internal factors that are unique to individuals, such as physiology, age, body morphology, and an individual’s genome; ii) General external factors, which includes socioeconomic condition, sociodemographic factors, and place of residence; and iii) Specific external factors, such as diet, lifestyle, environmental and occupational exposures, among others.

We welcome manuscripts on:

(i) Exposome-related approaches such as systems biology, high-performance toxicological screening, temporal and spatial statistical models;

(ii) Translation of the importance of environmental factors in diseases using principles of exposome;

(iii) New scientific findings to boost and improve sustainability, prevention, or treatment strategies in humans;

(iv) Characterizing of the internal exposome at the individual level by integrating data – omics (transcriptomics, proteomics, metabolomics, microbiomics) and monitoring;

(v) Scientific guidance on risk assessment based on exposome;

(vi) Understanding how general and specific external factors influence the risk of chronic diseases.


Keywords: exposome, proteomics, metabolomics, microbiomics, transcriptomics, environmental factors, toxicological screening


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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