About this Research Topic
Viral outbreaks are a serious concern since they are an impediment to the development, productivity, and profitability of aquatic organisms in the aquaculture industry. The main defense mechanism in fish and shellfish is innate immunity, which is the most ancient defense and works efficiently to defend organisms against microbial infections. The innate immune system constitutes the initial mechanisms of response to infection and comprises a set of cells and molecules which are involved in the body's defense against infection. In addition, vertebrates count on the adaptive immune system, which is principally based on immune memory. However, lower vertebrates possess a less developed adaptive immune response as compared to higher vertebrates and therefore, heavily rely on innate immune defenses for the control of pathogens.
The aim of this Research Topic is to collect the recent advances in the current understanding of the immune responses against viral infections in fish and shellfish organisms. Our objective is to broaden the interest of research communities towards these areas of research and direct this knowledge into new perspectives and strategies related to antiviral defense across fish and shellfish organisms.
This Research Topic will be dedicated to an overview of the recent progress in the study of the antiviral immune responses of aquatic organisms including:
1. Antiviral mechanisms of innate immunity in fish and shellfish.
2. Antiviral determinants and molecules responsible for defense mechanisms.
3. Antiviral mechanisms of adaptive immunity in fish.
4. Molecular regulation of innate immune responses upon viral infection.
5. Molecular regulation of adaptive immune response in fish upon viral infection.
6. Mucosal innate immunity-related to the antiviral response.
7. Cellular response of viral infections in fish and shellfish.
8. Innate immune cytokine/chemokine receptors and downstream signaling.
9. Comparative study of the antiviral immune response elicited by fish and shellfish.
We welcome the submission of Original Research, Review, and Mini-Review articles covering the above-mentioned subtopics.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.