Filamentous fungi play important roles (i) ecologically in global nutrient cycles as primary decomposers, (ii) industrially as fermenters, enzyme and metabolite producers, (iii) agriculturally as plant pathogens and toxin producers, and (iv) medically as allergen producers and pathogens. Thus, identifying genes and genetic variants underlying traits in filamentous fungi is of great importance. Genomic approaches are essential tools when investigating the association between genotype and phenotype. For example, comparative, population, and quantitative genomic approaches are used to identify divergent genomic regions, signatures of recent positive selection, and genetic variants statistically associated with particular traits. These approaches have yielded, and will continue to provide, key insights into the biology of filamentous fungi.
Understanding the genomic basis of phenotypes is the main goal of evolutionary genetics. The continued emergence of affordable, high-quality DNA sequencing has made genomics an accessible and indispensable tool. Additionally, recent advances in long-read DNA sequencing are enabling the characterization of complex structural variants. The goal of this Research Topic is to highlight established and novel genomic and bioinformatics approaches used to shed light on the roots of filamentous fungal phenotypes.
This Research Topic will address insights into the genetic underpinnings of phenotypes in filamentous fungi gained through genomics, and their bioinformatic approaches. Subjects related to the genomics of model and non-model filamentous fungi are welcome including:
- Comparative genomics of phenotypically distinct organisms.
- Population genomics of phenotypically divergent populations.
- Genome-wide association analysis.
- Quantitative trait loci (QTL) analysis.
- Bulked segregant analysis.
- Experimental evolution coupled to sequencing.
Filamentous fungi play important roles (i) ecologically in global nutrient cycles as primary decomposers, (ii) industrially as fermenters, enzyme and metabolite producers, (iii) agriculturally as plant pathogens and toxin producers, and (iv) medically as allergen producers and pathogens. Thus, identifying genes and genetic variants underlying traits in filamentous fungi is of great importance. Genomic approaches are essential tools when investigating the association between genotype and phenotype. For example, comparative, population, and quantitative genomic approaches are used to identify divergent genomic regions, signatures of recent positive selection, and genetic variants statistically associated with particular traits. These approaches have yielded, and will continue to provide, key insights into the biology of filamentous fungi.
Understanding the genomic basis of phenotypes is the main goal of evolutionary genetics. The continued emergence of affordable, high-quality DNA sequencing has made genomics an accessible and indispensable tool. Additionally, recent advances in long-read DNA sequencing are enabling the characterization of complex structural variants. The goal of this Research Topic is to highlight established and novel genomic and bioinformatics approaches used to shed light on the roots of filamentous fungal phenotypes.
This Research Topic will address insights into the genetic underpinnings of phenotypes in filamentous fungi gained through genomics, and their bioinformatic approaches. Subjects related to the genomics of model and non-model filamentous fungi are welcome including:
- Comparative genomics of phenotypically distinct organisms.
- Population genomics of phenotypically divergent populations.
- Genome-wide association analysis.
- Quantitative trait loci (QTL) analysis.
- Bulked segregant analysis.
- Experimental evolution coupled to sequencing.
