About this Research Topic
The striatum has been divided into different functional neuronal groups using three major factors: region (dorsolateral, ventromeial etc.), compartment (striosome and matrix) and dopamine receptor dominance (D1 and D2). Each of these dimensions of heterogeneity has been extensively studied, but combinations of two or more factors have been given little attention. For example little is known about afferent/efferent connections of D2 dopamine receptor dominant neurons in the striosomes. This Research Topic welcomes articles stressing the heterogeneity observed in neuroanatomy, microcircuits, synaptology, electrophysiology, genetic profiles or functional organization of striatal neurons in health, disease and under medication.
Although contributions addressing any single dimension of the striatal heterogeneity are welcome, special interest is given to the research taking into account two or three dimensions of heterogeneity. Original research using different animal models or computational modeling as well as hypotheses, theories and reviews are encouraged to contribute to this edition.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.