Research Topic

The Clinical Relevance of Cellular and Network Integration in Cardiorespiratory Control

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About this Research Topic

Cardiorespiratory control is continuously adapted to changes in the metabolic, environmental, behavioral and developmental conditions of an organism. Any factor altering cardiorespiratory control can become detrimental to the organism, thus making cardiorespiratory control a core issue in Physiology and ...

Cardiorespiratory control is continuously adapted to changes in the metabolic, environmental, behavioral and developmental conditions of an organism. Any factor altering cardiorespiratory control can become detrimental to the organism, thus making cardiorespiratory control a core issue in Physiology and Pathophysiology. This Research Topic will highlight the cellular and network mechanisms that underlie cardiorespiratory control and their clinical implications. Recent advances in neurobiology have provided novel insights into the cellular and network mechanisms that underlie cardiorespiratory control. The use of slices, in situ and in vivo preparations, combined with modern genetic, molecular and optogenetic techniques have lead to a new level of understanding of the mechanisms that govern not only the normal physiological integration of cardiovascular and respiratory functions, but also the mechanisms that lead to pathologies such as those seen in sleep apnea, hypertension, CCHS or Sudden Infant Death Syndrome.


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