Research Topic

Neuroepidemiology of Stroke in Low and Middle Income Countries

About this Research Topic

From 1990 to 2010, there has been a decline in the incidence and mortality rates of stroke in high-income countries. On the contrary, in low and middle-income countries the incidence and mortality rates did not change and their absolute numbers increased. Over 75% of all stroke-related deaths occur in developing countries. China alone accounts for one-third of stroke mortality worldwide. The INTERSTROKE study of 2009 demonstrated that hypertension, diabetes mellitus, smoking, abdominal obesity, and physical inactivity are the principal risk factors for both hemorrhagic and ischemic strokes across all nations worldwide. Inadequacy in controlling these risk factors is the reason for the escalation of stroke in developing nations. The epidemiological parameters and outcomes showed variabilities depending on gender, ethnicity, geographical region, and urban-rural background.

This Research Topic aims to determine:
1. The current epidemiological parameters of stroke and stroke-related disability-adjusted life years (DALYs)
2. The secular trend of stroke over the last decade
3. Novel strategies to control the risk factors of stroke
4. Utilisation of thrombolytic therapy in acute ischemic stroke in resource-limited nations

The above data will give us comprehensive knowledge of the current global burden of stroke. The data is invaluable to allow evidence-based health care planning for this very important disorder, which is a leading cause of death and disability worldwide.

The Editors aim to receive articles in the form of original epidemiological research on stroke, particularly from middle- and low-income countries where data is still lacking. Review articles and commentaries are also welcome.


Keywords: Stroke, Incidence, Mortality, Low-Middle Income Countries, Thrombolysis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

From 1990 to 2010, there has been a decline in the incidence and mortality rates of stroke in high-income countries. On the contrary, in low and middle-income countries the incidence and mortality rates did not change and their absolute numbers increased. Over 75% of all stroke-related deaths occur in developing countries. China alone accounts for one-third of stroke mortality worldwide. The INTERSTROKE study of 2009 demonstrated that hypertension, diabetes mellitus, smoking, abdominal obesity, and physical inactivity are the principal risk factors for both hemorrhagic and ischemic strokes across all nations worldwide. Inadequacy in controlling these risk factors is the reason for the escalation of stroke in developing nations. The epidemiological parameters and outcomes showed variabilities depending on gender, ethnicity, geographical region, and urban-rural background.

This Research Topic aims to determine:
1. The current epidemiological parameters of stroke and stroke-related disability-adjusted life years (DALYs)
2. The secular trend of stroke over the last decade
3. Novel strategies to control the risk factors of stroke
4. Utilisation of thrombolytic therapy in acute ischemic stroke in resource-limited nations

The above data will give us comprehensive knowledge of the current global burden of stroke. The data is invaluable to allow evidence-based health care planning for this very important disorder, which is a leading cause of death and disability worldwide.

The Editors aim to receive articles in the form of original epidemiological research on stroke, particularly from middle- and low-income countries where data is still lacking. Review articles and commentaries are also welcome.


Keywords: Stroke, Incidence, Mortality, Low-Middle Income Countries, Thrombolysis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

21 August 2021 Abstract
19 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

21 August 2021 Abstract
19 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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