About this Research Topic
Pharmacometrics is the core of MIDD, aimed at establishing models to provide guidance and decision support in drug development such as efficacy comparisons, dosage regimen optimization and endpoint analysis. Over the last decade, there is an increased application of pharmacometric methodologies in drug development and applied pharmacotherapy by industry, academia and especially regulatory agencies. This Research Topic focuses on providing a platform for pharmacometricians to share their cutting-edge works and for academic scientists to share new modelling strategies and methodologies.
The aim of the current Research Topic is to cover promising, recent, and novel research trends in model-informed drug discovery and development. Areas to be covered in this Research Topic may include, but are not limited to:
• Model-informed Drug Development,
• Model-informed Precision Dosing Quantitative Systems Pharmacology,
• Physiologically-based Pharmacokinetics Model,
• Systems Biology Model
• Clinical reports
• Evidence-based mechanopharmacology
To be considered for review in the specialty section Translational Pharmacology submissions cannot be based on purely in silico work.
Keywords: Pharmacometrics, Drug development, Clinical observations, Advanced analysis tools, Cellular and molecular mechanics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.