Behavioural dysfunctions (e.g., social withdrawal, depression, aggressiveness, anhedonia), as pathophysiologically relevant constructs representing specific domains of human functioning, are core features of different neuropsychiatric disorders, significantly affecting the quality of life of patients and their caregivers. In this regard, the paucity of therapeutic treatments, aiming to restore such behavioural deficits, highlights the need to disentangle the underlying mechanisms that give rise to these behavioural dysfunctions, commonly occurring in several neuropsychiatric diseases.
The goal of this Research Topic is to investigate different behavioural impairments, such as social withdrawal, depression, aggressiveness, anhedonia, often occurring in several neuropsychiatric diseases, aiming to unravel the underlying neurobiology and further identify new possible therapeutic candidates. To this purpose, common biological alterations resulting in the above-mentioned behavioural dysfunctions shared across different neuropsychiatric diseases might represent new interesting and innovative therapeutic targets.
We welcome research papers reporting Original Research from preclinical and clinical studies and Review papers.
Topics may include:
• Etiopathology of behavioural dysfunctions commonly occurring in neuropsychiatric disorders and possible therapeutic targets;
• Novel possible therapeutic treatments in animal models of neuropsychiatric diseases;
• Clinical studies regarding possible future therapeutic treatments of behavioural symptoms typically occurring in psychiatric patients;
• Preclinical and clinical studies aiming to explore common biological targets across different neuropsychiatric diseases as new possible therapeutic candidates;
• Review articles describing and summarizing the state of the art of innovative therapeutic treatments of different behavioural dysfunctions shared across several neuropsychiatric disorders.
Behavioural dysfunctions (e.g., social withdrawal, depression, aggressiveness, anhedonia), as pathophysiologically relevant constructs representing specific domains of human functioning, are core features of different neuropsychiatric disorders, significantly affecting the quality of life of patients and their caregivers. In this regard, the paucity of therapeutic treatments, aiming to restore such behavioural deficits, highlights the need to disentangle the underlying mechanisms that give rise to these behavioural dysfunctions, commonly occurring in several neuropsychiatric diseases.
The goal of this Research Topic is to investigate different behavioural impairments, such as social withdrawal, depression, aggressiveness, anhedonia, often occurring in several neuropsychiatric diseases, aiming to unravel the underlying neurobiology and further identify new possible therapeutic candidates. To this purpose, common biological alterations resulting in the above-mentioned behavioural dysfunctions shared across different neuropsychiatric diseases might represent new interesting and innovative therapeutic targets.
We welcome research papers reporting Original Research from preclinical and clinical studies and Review papers.
Topics may include:
• Etiopathology of behavioural dysfunctions commonly occurring in neuropsychiatric disorders and possible therapeutic targets;
• Novel possible therapeutic treatments in animal models of neuropsychiatric diseases;
• Clinical studies regarding possible future therapeutic treatments of behavioural symptoms typically occurring in psychiatric patients;
• Preclinical and clinical studies aiming to explore common biological targets across different neuropsychiatric diseases as new possible therapeutic candidates;
• Review articles describing and summarizing the state of the art of innovative therapeutic treatments of different behavioural dysfunctions shared across several neuropsychiatric disorders.
