Genetic effects, epigenetic mechanisms, and nutritional factors contribute to sex- and gender differences of endocrine, metabolic and musculoskeletal disorders. Sexual dysmorphism is considered a priority within the spectrum of bone research, as the musculoskeletal system is one of the areas in which sexual dysmorphism is most striking. Males and females show biological differences at multiple levels, and sex differences in bone mass and structure are well recognized, reflecting distinct actions of different sex steroids.
Males and females suffer from diseases in different ways. Understanding the sex differences in the musculoskeletal system and how this is differentially regulated by steroid hormones, is critical for optimizing patient care. With this Research Topic, we aim to explore what we know about the sexual differences and the role that the steroid hormones play in the musculoskeletal system.
We welcome submissions of studies ranging from molecular, cellular, systems, and whole-body function. Topics of interest include, but are not limited to:
- Sex differences in hormone levels and their impact on musculoskeletal diseases
- Sex differences in musculoskeletal structures
- Sex steroids action in musculoskeletal health
- Sex specific strategies for the prevention and treatment of musculoskeletal diseases
Genetic effects, epigenetic mechanisms, and nutritional factors contribute to sex- and gender differences of endocrine, metabolic and musculoskeletal disorders. Sexual dysmorphism is considered a priority within the spectrum of bone research, as the musculoskeletal system is one of the areas in which sexual dysmorphism is most striking. Males and females show biological differences at multiple levels, and sex differences in bone mass and structure are well recognized, reflecting distinct actions of different sex steroids.
Males and females suffer from diseases in different ways. Understanding the sex differences in the musculoskeletal system and how this is differentially regulated by steroid hormones, is critical for optimizing patient care. With this Research Topic, we aim to explore what we know about the sexual differences and the role that the steroid hormones play in the musculoskeletal system.
We welcome submissions of studies ranging from molecular, cellular, systems, and whole-body function. Topics of interest include, but are not limited to:
- Sex differences in hormone levels and their impact on musculoskeletal diseases
- Sex differences in musculoskeletal structures
- Sex steroids action in musculoskeletal health
- Sex specific strategies for the prevention and treatment of musculoskeletal diseases
