A growing number of individuals aged 65 and older are living with diabetes, whether they were diagnosed earlier in life or became diabetic as they aged. An even larger number of older adults are believed to be living with prediabetes. With humans living longer than ever and the world's aging population expected to increase in the coming decades, the diagnosis, management, and treatment of diabetes in an aging population presents a public health crisis in-the-making. It is crucial that our understanding of the relationship between diabetes and the aging process advances with it. While Type 2 diabetes mellitus (T2DM) is typically associated with aging, an alarming number of type 1 diabetes patients are being diagnosed later in life. In fact, the fastest growing population of new onset T1DM occurs after age 40. The American Diabetes Association reports that misdiagnosis of diabetes, either type 1 called type 2 due to age or type 2 called type 1 due to age, ranges from 28–35%.
Diabetes, whether type 1 or type 2, presents a number of symptoms and comorbidities which are often exacerbated in the aging population regardless of a patients age at initial diagnosis, such as insulin resistance and glycemic dysregulation, cardiovascular complications, and cognitive decline. In fact, cardiologists do not distinguish T1DM and T2DM when considering cardiovascular comorbidities. Insulin resistance and glycemic dysregulation in particular can manifest and effect numerous other systems, a problem of growing concern for those older adults with multiple coexisting medical conditions.
This Research Topic will compile original research, reviews, and mini reviews on the relationship between type 1 and type 2 diabetes and the aging process. Manuscripts on the role of mitochondria in aging in patients with diabetes, as well as effects of insulin regulation and glycemic control as they relate to cardiovascular and cognitive symptoms are of particular interest. Biomarkers to distinguish type 1/type 2 and/or biomarkers for comorbidities associated with diabetes are of high interest. A greater understanding of the pathogenesis of insulin resistance and glycemic control during the aging process will improve clinical application and treatment for older adults living with diabetes as well as managing the prediabetic condition in others.
A growing number of individuals aged 65 and older are living with diabetes, whether they were diagnosed earlier in life or became diabetic as they aged. An even larger number of older adults are believed to be living with prediabetes. With humans living longer than ever and the world's aging population expected to increase in the coming decades, the diagnosis, management, and treatment of diabetes in an aging population presents a public health crisis in-the-making. It is crucial that our understanding of the relationship between diabetes and the aging process advances with it. While Type 2 diabetes mellitus (T2DM) is typically associated with aging, an alarming number of type 1 diabetes patients are being diagnosed later in life. In fact, the fastest growing population of new onset T1DM occurs after age 40. The American Diabetes Association reports that misdiagnosis of diabetes, either type 1 called type 2 due to age or type 2 called type 1 due to age, ranges from 28–35%.
Diabetes, whether type 1 or type 2, presents a number of symptoms and comorbidities which are often exacerbated in the aging population regardless of a patients age at initial diagnosis, such as insulin resistance and glycemic dysregulation, cardiovascular complications, and cognitive decline. In fact, cardiologists do not distinguish T1DM and T2DM when considering cardiovascular comorbidities. Insulin resistance and glycemic dysregulation in particular can manifest and effect numerous other systems, a problem of growing concern for those older adults with multiple coexisting medical conditions.
This Research Topic will compile original research, reviews, and mini reviews on the relationship between type 1 and type 2 diabetes and the aging process. Manuscripts on the role of mitochondria in aging in patients with diabetes, as well as effects of insulin regulation and glycemic control as they relate to cardiovascular and cognitive symptoms are of particular interest. Biomarkers to distinguish type 1/type 2 and/or biomarkers for comorbidities associated with diabetes are of high interest. A greater understanding of the pathogenesis of insulin resistance and glycemic control during the aging process will improve clinical application and treatment for older adults living with diabetes as well as managing the prediabetic condition in others.