COVID-19 presents a wide spectrum of clinical manifestations; it ranges from an asymptomatic infection to a severe pneumonia or multisystemic failure. The relationship between immunity, together with inflammation and endothelial damage seems to favor the evolution to organic damage and a poor prognosis. However nearly two years after the pandemic, it is known that there are persistent forms of COVID-19 with medium-term affectation in different organs and systems that significantly affect the quality of life of many convalescent patients. The exact mechanisms are not yet well delimited.
In this Resarch Topic, we want to encourage leading researchers to share their more recent original findings on COVID-19 with the scientific community in a holistic way; they wil be related to the immunopathogenesis of the virus to the occurrence of organ damage. Special attention will be paid to the relationship between these inflammatory and immunoglogic alterations present in the patients (immunophenotypes) with the development of organic complications not only in the short term, but in the medium/long term, as well as with the treatments received.
Original articles related to immunopathogenesis of COVID-19, novel biomarkers related to COVID-19 prognosis and complications, organ damage in those affected in the medium or long term, and related treatments in COVID-19 will be welcomed.
Original research works will be prioritized, especially clinical trials, but systematic reviews/mini-reviews and case studies will also be considered.
COVID-19 presents a wide spectrum of clinical manifestations; it ranges from an asymptomatic infection to a severe pneumonia or multisystemic failure. The relationship between immunity, together with inflammation and endothelial damage seems to favor the evolution to organic damage and a poor prognosis. However nearly two years after the pandemic, it is known that there are persistent forms of COVID-19 with medium-term affectation in different organs and systems that significantly affect the quality of life of many convalescent patients. The exact mechanisms are not yet well delimited.
In this Resarch Topic, we want to encourage leading researchers to share their more recent original findings on COVID-19 with the scientific community in a holistic way; they wil be related to the immunopathogenesis of the virus to the occurrence of organ damage. Special attention will be paid to the relationship between these inflammatory and immunoglogic alterations present in the patients (immunophenotypes) with the development of organic complications not only in the short term, but in the medium/long term, as well as with the treatments received.
Original articles related to immunopathogenesis of COVID-19, novel biomarkers related to COVID-19 prognosis and complications, organ damage in those affected in the medium or long term, and related treatments in COVID-19 will be welcomed.
Original research works will be prioritized, especially clinical trials, but systematic reviews/mini-reviews and case studies will also be considered.
