Neuroendocrinology is the study of interactions between the nervous and endocrine systems. Classical neuroendocrine studies have focused on the hypothalamo–adenohypophyseal axis and the hypothalamic–neurohypophysial system, and produced a variety of principles that are still the foundation of modern neuroendocrinology. Over the past decades, with the introduction of many powerful bio-techniques and novel research ideas, considerable progress has been achieved in understanding the neuroendocrine system and neurohormone. Many novel neuropeptides are identified within the brain that influence a wide range of social and non-social behaviors, and within varieties of tissues to exert autocrine, paracrine and even intracrine functions, such as brain-gut peptides and immunological peptides from the thymus. Correspondingly, modern neuroendocrinology embraces a wide range of topics from genetic and epigenetic features of neuroendocrine cells, receptors and their signaling mechanism, identification of novel neuropeptides and their functions, neuroendocrine basis of social behaviors and cognition, interaction between neuroendocrine/endocrine system and other organ systems, reciprocal brain-body communication, neuroendocrine regulation under varieties of physiological and pathological conditions, computational neuroendocrinology, to artificially engineering neuroendocrine organs and translational studies of these hormones. However, neuroendocrine researchers still face the challenges of many neuroendocrine diseases, such as hyperthyroidism, infertility, hypertension, hyponatremia, obesity, diabetes mellitus, breastfeeding failure, stress, mental retardation, psychiatric disorders, endocrine tumors and prevention of COVID-19 from the view of endocrine regulation. It is beyond all doubt that Chinese scholars alongside international neuroendocrinologists have contributed significantly to the neuroendocrine knowledge by continuously creating novel approaches, concepts and principles in both basic research and clinical application.
Based on the success of the first edition of the research topic on “Neuroendocrine Research in Health and Disease” that has 23 papers published with great impact to the neuroendocrine studies, we would like to provide this platform again to collect a broad assembly of papers including original research, perspectives and reviews, covering all issues of the regulation and functions of the (neuro)endocrine system. We believe that the new collection will facilitate interactions between Chinese and international neuroendocrinologists, promote the growth of neuroendocrine society and identify better strategy of prevention and treatment of neuroendocrine diseases. We welcome all neuroendocrine researchers join in our march for the future neuroendocrinology by submitting your research works and thoughts.
Neuroendocrinology is the study of interactions between the nervous and endocrine systems. Classical neuroendocrine studies have focused on the hypothalamo–adenohypophyseal axis and the hypothalamic–neurohypophysial system, and produced a variety of principles that are still the foundation of modern neuroendocrinology. Over the past decades, with the introduction of many powerful bio-techniques and novel research ideas, considerable progress has been achieved in understanding the neuroendocrine system and neurohormone. Many novel neuropeptides are identified within the brain that influence a wide range of social and non-social behaviors, and within varieties of tissues to exert autocrine, paracrine and even intracrine functions, such as brain-gut peptides and immunological peptides from the thymus. Correspondingly, modern neuroendocrinology embraces a wide range of topics from genetic and epigenetic features of neuroendocrine cells, receptors and their signaling mechanism, identification of novel neuropeptides and their functions, neuroendocrine basis of social behaviors and cognition, interaction between neuroendocrine/endocrine system and other organ systems, reciprocal brain-body communication, neuroendocrine regulation under varieties of physiological and pathological conditions, computational neuroendocrinology, to artificially engineering neuroendocrine organs and translational studies of these hormones. However, neuroendocrine researchers still face the challenges of many neuroendocrine diseases, such as hyperthyroidism, infertility, hypertension, hyponatremia, obesity, diabetes mellitus, breastfeeding failure, stress, mental retardation, psychiatric disorders, endocrine tumors and prevention of COVID-19 from the view of endocrine regulation. It is beyond all doubt that Chinese scholars alongside international neuroendocrinologists have contributed significantly to the neuroendocrine knowledge by continuously creating novel approaches, concepts and principles in both basic research and clinical application.
Based on the success of the first edition of the research topic on “Neuroendocrine Research in Health and Disease” that has 23 papers published with great impact to the neuroendocrine studies, we would like to provide this platform again to collect a broad assembly of papers including original research, perspectives and reviews, covering all issues of the regulation and functions of the (neuro)endocrine system. We believe that the new collection will facilitate interactions between Chinese and international neuroendocrinologists, promote the growth of neuroendocrine society and identify better strategy of prevention and treatment of neuroendocrine diseases. We welcome all neuroendocrine researchers join in our march for the future neuroendocrinology by submitting your research works and thoughts.
