About this Research Topic
In PAD, research of new materials could help the amelioration of long term patency while at the same time reducing the infectious risk. The increasing number of hemodialysis patients in this field was the driving force for the rapid development of adequate vessel substitutes in order to provide long term treatments while preserving the patient’s vascular heritage. This special issue should be considered a real update both for clinical vascular surgeons and for those who are also involved in this research field.
The thoracic aorta, in particular at its arch, represents undoubtedly the first obstacle to be resolved. The remodelling of the aorta after the insertion of an endograft, especially in a dissection pattern, allows long term observation to foresee and program a correct approach to appearing pathology and a valid understanding of the wall alterations or any variations which occur as a result of the aorta-graft complex in the months and/or years following the operation.
In this field, the bioengineering approach can be helpful in order to better understand the causes of some short or long term complications. Furthermore, because of the increasing number of peripheral arteriopathies, its surgical approach and treatment require an update on the use of these materials, because many patients come to clinical observation with a scarcity of their own venous material, which usually represents the best vascular substitute for a good outcome of the surgery.
Vascular access in patients with renal insufficiency in more and more numerous cases, requires prolonged hemodialytic treatment and a consequent amelioration or even substitution of the native access. It appears with clear evidence how a strict collaboration between the vascular surgeon and the bioengineer is mandatory in order to offer to the patients an improvement both of their life duration and quality.
Therefore, the aim of this special issue is to collect the latest proposals in the field of biomaterials and at the same time to allow the deepening of the study of the system artery-graft.
Manuscripts focusing on the below will be accepted into this Research Topic:
1) Physical forces inside the grafting material and their clinical application in Arterial Aneurysms and Arterial Dissections.
2) Middle and long term complications both of endografts and substituting grafts in the territory of the thoracic and abdominal aorta.
3) New materials in peripheral arterial surgery and the vascular access surgery.
4) Evolution and natural history of autologous and prosthetic vascular access and what their future could be from an engineering perspective.
Keywords: vascular, bioengineering, graft, endoprosthesis, silk, material, aorta, CLTI
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.