Updates on Giant Cell Arteritis: Pathogenesis, Diagnosis and Treatment

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Andreas P Diamantopoulos

Akershus University Hospital

Stavros Chrysidis

Sydvestjysk Sygehus

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Giant cell arteritis (GCA) or 'temporal arteritis’ symptoms include a new headache around the temples as well as the front, top and back of the skull. Other common symptoms include fatigue, weight-loss, an unexplained fever and can include pains in the jaw, throat and tongue, double vision and eventually blindness. Blindness resulting from GCA can occur suddenly however early treatment can prevent this.

While there is no simple diagnosis for GCA, ultrasound has recently emerged as a leading diagnostic resource for early detection of this severe condition. High dose corticosteroid treatment is still the mainstream of treatment but IL6 inhibition has provided new opportunities to these patients and has also challenged classic treatment algorithms.

This Research Topic aims to provide an update on the pathogenesis, diagnosis and treatment of GCA in order to improve patient outcomes.

Giant cell arteritis (GCA) or 'temporal arteritis’ symptoms include a new headache around the temples as well as the front, top and back of the skull. Other common symptoms include fatigue, weight-loss, an unexplained fever and can include pains in the jaw, throat and tongue, double vision and eventually blindness. Blindness resulting from GCA can occur suddenly however early treatment can prevent this.

While there is no simple diagnosis for GCA, ultrasound has recently emerged as a leading diagnostic resource for early detection of this severe condition. High dose corticosteroid treatment is still the mainstream of treatment but IL6 inhibition has provided new opportunities to these patients and has also challenged classic treatment algorithms.

This Research Topic aims to provide an update on the pathogenesis, diagnosis and treatment of GCA in order to improve patient outcomes.

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Editors

Andreas P Diamantopoulos

Akershus University Hospital

Stavros Chrysidis

Sydvestjysk Sygehus

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Frontiers in Medicine

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