Acute respiratory distress syndrome (ARDS) and sepsis remain leading causes of patient morbidity and mortality and the COVID-19 pandemic has highlighted the continuing lack of effective therapeutic options for these and other related acute inflammatory conditions. Recently, a host of novel medicinal approaches have been investigated to address this problem, such as advances in the development of pharmacological agents, recombinant protein drugs and cell and gene therapies. Bioinformatics based approaches and clinical profiling of patients are also paving the way for stratification, targeted therapies and precision medicines. Given recent exciting work in this field, this is a timely opportunity to showcase exciting advances in the field of critical care medicine, particularly those relying on paradigm shifting modalities and outside-the-box approaches to address this family of devastating conditions.
Efficient therapies for ARDS and sepsis remain elusive despite several advances in the field. What recent progress have we made to combat this? Are we close to a viable therapy?
In this research topic we will be accepting primary research and review articles that address the following themes:
- Studies examining disease mechanisms/states/markers in ARDS and Sepsis
- Studies that have identified novel targets for therapy
- Patient profiling or data re-analysis studies
- Studies aimed at enhancing precision medicines
- Recent advances in pharmacological, gene or cell therapies
Acute respiratory distress syndrome (ARDS) and sepsis remain leading causes of patient morbidity and mortality and the COVID-19 pandemic has highlighted the continuing lack of effective therapeutic options for these and other related acute inflammatory conditions. Recently, a host of novel medicinal approaches have been investigated to address this problem, such as advances in the development of pharmacological agents, recombinant protein drugs and cell and gene therapies. Bioinformatics based approaches and clinical profiling of patients are also paving the way for stratification, targeted therapies and precision medicines. Given recent exciting work in this field, this is a timely opportunity to showcase exciting advances in the field of critical care medicine, particularly those relying on paradigm shifting modalities and outside-the-box approaches to address this family of devastating conditions.
Efficient therapies for ARDS and sepsis remain elusive despite several advances in the field. What recent progress have we made to combat this? Are we close to a viable therapy?
In this research topic we will be accepting primary research and review articles that address the following themes:
- Studies examining disease mechanisms/states/markers in ARDS and Sepsis
- Studies that have identified novel targets for therapy
- Patient profiling or data re-analysis studies
- Studies aimed at enhancing precision medicines
- Recent advances in pharmacological, gene or cell therapies