Hypoxia is a condition that affects thousands of people around the world every day. It impacts numerous physiological and molecular mechanisms such as hemodynamics, cognitive function, oncological changes, adaptation to inflammatory processes, and other aspects. Interestingly, individual adaptability to hypoxia varies widely. This affects not only patients but also healthy individuals. Not least, genetically different preconditions could be responsible for this. These individual differences are also responsible for the different response to drug therapy, disease severity and progression. However, hypoxia is often only one aspect of a more complex problem. The combination, e.g. with inflammation or physical exercise, can cause completely different reactions of the body. Last but not least, the question is whether hypoxia is always harmful or whether it can also be protective. This question is also the subject of current scientific work.
With this special issue, we would like to provide interested scientists with an interdisciplinary and translational overview of the current state of research in the field of hypoxia. The aim is to expand one's own research beyond one's own field of expertise and to give ideas for future scientific questions and projects and, if necessary, to establish contacts with other working groups. This applies to experimental, molecular and also clinical scientists.
Scope of the research topic is to focus on novel aspects of hypoxia and hypoxic-inflammatory processes form all fields of clinical and experimental medicine. We would like to invite scientists to submit translational work which gives new insights on effects of hypoxia on critically ill patients (e.g. sepsis, ARDS or COVID-19), solid organ transplantation, reperfusion injury, tumor progression or healthy volunteers (e.g. mountaineers). In addition, we are interested in work dealing with the identification of high-risk subjects (e.g. concerning perioperative medicine, delirium, cognitive deficits, acute mountain sickness) and the development of individualized prophylaxis and treatment pathways.
Possible types of manuscripts are original articles (humans and animals), short communications, reviews and meta-analyses.
Hypoxia is a condition that affects thousands of people around the world every day. It impacts numerous physiological and molecular mechanisms such as hemodynamics, cognitive function, oncological changes, adaptation to inflammatory processes, and other aspects. Interestingly, individual adaptability to hypoxia varies widely. This affects not only patients but also healthy individuals. Not least, genetically different preconditions could be responsible for this. These individual differences are also responsible for the different response to drug therapy, disease severity and progression. However, hypoxia is often only one aspect of a more complex problem. The combination, e.g. with inflammation or physical exercise, can cause completely different reactions of the body. Last but not least, the question is whether hypoxia is always harmful or whether it can also be protective. This question is also the subject of current scientific work.
With this special issue, we would like to provide interested scientists with an interdisciplinary and translational overview of the current state of research in the field of hypoxia. The aim is to expand one's own research beyond one's own field of expertise and to give ideas for future scientific questions and projects and, if necessary, to establish contacts with other working groups. This applies to experimental, molecular and also clinical scientists.
Scope of the research topic is to focus on novel aspects of hypoxia and hypoxic-inflammatory processes form all fields of clinical and experimental medicine. We would like to invite scientists to submit translational work which gives new insights on effects of hypoxia on critically ill patients (e.g. sepsis, ARDS or COVID-19), solid organ transplantation, reperfusion injury, tumor progression or healthy volunteers (e.g. mountaineers). In addition, we are interested in work dealing with the identification of high-risk subjects (e.g. concerning perioperative medicine, delirium, cognitive deficits, acute mountain sickness) and the development of individualized prophylaxis and treatment pathways.
Possible types of manuscripts are original articles (humans and animals), short communications, reviews and meta-analyses.
