About this Research Topic
PTSD is a major debilitating disorder the neural mechanisms of which are being intensely investigated but not yet understood. There are several avenues of research, including structural and functional MRI, magnetoencephalography, neural network modeling, positron emission tomography, neurotransmitter research, etc. Several lines of research are currently attempting to investigate and answer crucial questions, including the following.
1.) What are the neural mechanisms leading to PTSD following trauma exposure?
2.) Which are the brain vulnerability factors that may predispose to developing PTSD?
3.) What are brain structural differences in PTSD (e.g. volumes of certain brain areas) as compared to healthy people and other disorders?
4.) What are brain functional differences in PTSD as compared to healthy people and people with other disorders?
5.) What methods are available for investigating brain structure and function in PTSD? In what kind of innovative ways are these methods being employed and combined to elucidate the neural basis of PTSD?
6.) How do neural mechanisms of PTSD inform diagnostic nosology?
7.) Why is PTSD commonly associated with many comorbidities?
8.) What are current theoretical frameworks for PTSD?
9.) What are possible neurotransmitter abnormalities in PTSD and how do they relate to its diverse symptomatology and symptom severity?
10.) What are the neural mechanisms underlying the differential effectiveness of various treatments for PTSD?
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