Animal development is the process that follows the fusion of male and female gametes derived from the parent generation, including cleavage, differentiation, gastrulation, organogenesis, growth, aging, and death. Though the processes show broad similarities, but also have crucial species-specificities in the transcriptome, proteome, and epigenome-mediated Spatio-temporal regulation. However, it has long been enigmatic how the multi-Omics are globally interrelated and function during animal development at the molecular level. Recent advances in high-throughput detection strategies contribute to the increased knowledge of DNA and RNA functions and their modifications.
In the Research Topic, we will focus on high-throughput detection methods and biological findings and discussion questions to be addressed during animal development. The multi-Omics, including transcriptome, proteome, and epigenome, are globally interrelated to control the process of animal development at the molecular level. However, it is far away to be addressed. We aim to focus on the biological findings associated with the regulatory roles of DNA and RNA modifications and functional genes on specific events during animal development. The high-throughput sequencing and bioinformatics combined with advanced computational analysis are appreciated, such as RNA-seq, small RNA-seq, ATAC-seq, WGBS, RRBS-seq, ChIP-seq, and exome-seq.
Potential subjects include, but are not limited to:
• Studies on the early embryos to stem cells
• Studies on morphogenesis to neurodevelopment and organogenesis
• Multi-Omics studies on genetics and epigenetics during animal development
Animal development is the process that follows the fusion of male and female gametes derived from the parent generation, including cleavage, differentiation, gastrulation, organogenesis, growth, aging, and death. Though the processes show broad similarities, but also have crucial species-specificities in the transcriptome, proteome, and epigenome-mediated Spatio-temporal regulation. However, it has long been enigmatic how the multi-Omics are globally interrelated and function during animal development at the molecular level. Recent advances in high-throughput detection strategies contribute to the increased knowledge of DNA and RNA functions and their modifications.
In the Research Topic, we will focus on high-throughput detection methods and biological findings and discussion questions to be addressed during animal development. The multi-Omics, including transcriptome, proteome, and epigenome, are globally interrelated to control the process of animal development at the molecular level. However, it is far away to be addressed. We aim to focus on the biological findings associated with the regulatory roles of DNA and RNA modifications and functional genes on specific events during animal development. The high-throughput sequencing and bioinformatics combined with advanced computational analysis are appreciated, such as RNA-seq, small RNA-seq, ATAC-seq, WGBS, RRBS-seq, ChIP-seq, and exome-seq.
Potential subjects include, but are not limited to:
• Studies on the early embryos to stem cells
• Studies on morphogenesis to neurodevelopment and organogenesis
• Multi-Omics studies on genetics and epigenetics during animal development
