Rheumatic diseases are a group of diseases that cause varying degrees of disability, involving bones, joints, muscles and surrounding soft tissues. In the last two decades, increasing research on rheumatic diseases has been conducted. Nevertheless, the etiology and pathogenesis of these diseases have not been fully elucidated. It is generally recognized that the onset and development of rheumatic diseases are the result of a combination of multiple factors, such as genetic, environmental and immune abnormalities, etc. Among these factors, the influence of immune abnormalities in rheumatic diseases has been extensively explored in depth nowadays. Moreover, as the influence of genetic and environmental factors on public health is gaining more attention, studies on the role of these two types of factors in rheumatic diseases have become an important direction.
On one hand, genetics is closely related to biological individuals. Within a large system, the discovery of relevant susceptibility genes will contribute to screening for high-risk populations, which is of theoretical significance and clinical application value for early warning, detection and individualized prevention of rheumatic diseases. On the other hand, environmental factors have been affecting human health directly or indirectly. Through identifying environmental risk factors for rheumatic diseases and exploring possible gene-environment interaction effects, establishment of comprehensive prevention strategies will be potentially and effectively facilitated. Therefore, efforts in these areas can contribute to important public health implications and the prevention and control of rheumatic diseases.
This Research Topic aims to discuss genetic and environmental factors of rheumatic diseases, including discovering new susceptibility genes and potential therapeutic targets, exploring the effects of environmental factors (e.g., air pollution, meteorological factors) on rheumatic diseases and interventions, as well as the impact of gene-environment interactions on rheumatic diseases. In addition, public health policies that address the prevention and treatment of rheumatic diseases for population health based on genetic and environmental factors are encouraged, as well as new ideas on the etiology and intervention of rheumatic diseases.
We welcome submissions of original research and review articles in the potential subtopics include but are not limited to the following:
• Exploration of potential susceptibility genes related to rheumatic diseases.
• Specific biomarkers for the development of rheumatic diseases.
• Association between air pollution and rheumatic diseases.
• Association between meteorological factors and rheumatic diseases.
• Influence of gene-environment interactions on the development of rheumatic diseases.
• Interventions for environmental influences on rheumatic diseases.
• Prevention and control strategies based on the role of genetics and environment in rheumatic diseases.
Rheumatic diseases are a group of diseases that cause varying degrees of disability, involving bones, joints, muscles and surrounding soft tissues. In the last two decades, increasing research on rheumatic diseases has been conducted. Nevertheless, the etiology and pathogenesis of these diseases have not been fully elucidated. It is generally recognized that the onset and development of rheumatic diseases are the result of a combination of multiple factors, such as genetic, environmental and immune abnormalities, etc. Among these factors, the influence of immune abnormalities in rheumatic diseases has been extensively explored in depth nowadays. Moreover, as the influence of genetic and environmental factors on public health is gaining more attention, studies on the role of these two types of factors in rheumatic diseases have become an important direction.
On one hand, genetics is closely related to biological individuals. Within a large system, the discovery of relevant susceptibility genes will contribute to screening for high-risk populations, which is of theoretical significance and clinical application value for early warning, detection and individualized prevention of rheumatic diseases. On the other hand, environmental factors have been affecting human health directly or indirectly. Through identifying environmental risk factors for rheumatic diseases and exploring possible gene-environment interaction effects, establishment of comprehensive prevention strategies will be potentially and effectively facilitated. Therefore, efforts in these areas can contribute to important public health implications and the prevention and control of rheumatic diseases.
This Research Topic aims to discuss genetic and environmental factors of rheumatic diseases, including discovering new susceptibility genes and potential therapeutic targets, exploring the effects of environmental factors (e.g., air pollution, meteorological factors) on rheumatic diseases and interventions, as well as the impact of gene-environment interactions on rheumatic diseases. In addition, public health policies that address the prevention and treatment of rheumatic diseases for population health based on genetic and environmental factors are encouraged, as well as new ideas on the etiology and intervention of rheumatic diseases.
We welcome submissions of original research and review articles in the potential subtopics include but are not limited to the following:
• Exploration of potential susceptibility genes related to rheumatic diseases.
• Specific biomarkers for the development of rheumatic diseases.
• Association between air pollution and rheumatic diseases.
• Association between meteorological factors and rheumatic diseases.
• Influence of gene-environment interactions on the development of rheumatic diseases.
• Interventions for environmental influences on rheumatic diseases.
• Prevention and control strategies based on the role of genetics and environment in rheumatic diseases.
