Autoinflammatory diseases still pose a challenge in the fields of their diagnosis and treatment. The pathogenesis of some is still not fully understood and concepts of their treatment have changed over the years.
Initially, modern therapies of autoinflammatory diseases were based on the use of synthetic drugs. Knowledge of their mechanisms, although well-established, isn't always sufficient to explain the full effect they exert. The invention of monoclonal antibody treatment and the introduction of biological drugs led to the identification of specific therapeutic targets. Now, the history of the treatment of autoinflammatory diseases comes full circle, with the realm of synthetic drugs once again revisited – this time to bring the emergence of synthetic targeted drugs, such as kinase inhibitors.
All these achievements allow us to look to the future of the management of autoinflammatory diseases with hope and optimism, although there is still a lot we need to learn about these illnesses and the most effective way to treat them. The proposed Research Topic aims to encourage submissions from clinicians and researchers regarding the issues and benefits of modern therapies, as well as perspectives in the treatment of autoinflammatory diseases. It is also an attempt to discuss the many problems still posed by autoinflammatory diseases. Submissions are welcome from all specialists interested in this subject.
Autoinflammatory diseases still pose a challenge in the fields of their diagnosis and treatment. The pathogenesis of some is still not fully understood and concepts of their treatment have changed over the years.
Initially, modern therapies of autoinflammatory diseases were based on the use of synthetic drugs. Knowledge of their mechanisms, although well-established, isn't always sufficient to explain the full effect they exert. The invention of monoclonal antibody treatment and the introduction of biological drugs led to the identification of specific therapeutic targets. Now, the history of the treatment of autoinflammatory diseases comes full circle, with the realm of synthetic drugs once again revisited – this time to bring the emergence of synthetic targeted drugs, such as kinase inhibitors.
All these achievements allow us to look to the future of the management of autoinflammatory diseases with hope and optimism, although there is still a lot we need to learn about these illnesses and the most effective way to treat them. The proposed Research Topic aims to encourage submissions from clinicians and researchers regarding the issues and benefits of modern therapies, as well as perspectives in the treatment of autoinflammatory diseases. It is also an attempt to discuss the many problems still posed by autoinflammatory diseases. Submissions are welcome from all specialists interested in this subject.
