Parturition is a complex process involving changes at the hormonal, physiological, morphological, immune, and metabolic levels. Preterm birth (PTB), defined as parturition occurring between 20 and 37 weeks of gestation, affects 11.1% of pregnancies worldwide. It is a major determinant of neonatal mortality and morbidity, often with long-term adverse effects on the health of both mother and child. In recent decades, the incidence of PTB has continued to rise in most countries. According to the World Health Organization, the rate of PTB across 184 countries is reported to be 5~18% of all births. Therefore, it is urgent to find ways to prevent preterm labor, and for this, a better understanding of the mechanisms behind it and those associated with parturition is necessary. Technological advances and efforts by scientists around the world are uncovering the mechanisms of parturition and preterm birth, helping us find more effective clinical interventions to prevent preterm birth and improve the outcome of parturition.
This Research Topic aims to investigate the mechanisms of parturition and preterm birth that are not well understood, and explore the unique roles of proteins or other molecules involved. Novel methods conducted in basic and clinical research to predict and regulate parturition and preterm birth are also encouraged.
We welcome submissions of Original Research, Reviews and Methodologies on the following sub-topics, including but not limited to:
• Parturition and endocrine regulation
• Parturition and immune regulation
• Metabolic remodeling at delivery
• Parturition and ion channels
• Important molecules and pathways in parturition
• Parturition and exosomes
• Epidemiological study of preterm birth
• Application advances of electromyometrial imaging (EMMI) and electromyography (EMG) in parturition research
• Novel methods employed in parturition research
• Novel tocolytic use in mono and combination therapy to mitigate preterm labor
• Novel clinical intervention methods for predicting and regulating the parturition
Parturition is a complex process involving changes at the hormonal, physiological, morphological, immune, and metabolic levels. Preterm birth (PTB), defined as parturition occurring between 20 and 37 weeks of gestation, affects 11.1% of pregnancies worldwide. It is a major determinant of neonatal mortality and morbidity, often with long-term adverse effects on the health of both mother and child. In recent decades, the incidence of PTB has continued to rise in most countries. According to the World Health Organization, the rate of PTB across 184 countries is reported to be 5~18% of all births. Therefore, it is urgent to find ways to prevent preterm labor, and for this, a better understanding of the mechanisms behind it and those associated with parturition is necessary. Technological advances and efforts by scientists around the world are uncovering the mechanisms of parturition and preterm birth, helping us find more effective clinical interventions to prevent preterm birth and improve the outcome of parturition.
This Research Topic aims to investigate the mechanisms of parturition and preterm birth that are not well understood, and explore the unique roles of proteins or other molecules involved. Novel methods conducted in basic and clinical research to predict and regulate parturition and preterm birth are also encouraged.
We welcome submissions of Original Research, Reviews and Methodologies on the following sub-topics, including but not limited to:
• Parturition and endocrine regulation
• Parturition and immune regulation
• Metabolic remodeling at delivery
• Parturition and ion channels
• Important molecules and pathways in parturition
• Parturition and exosomes
• Epidemiological study of preterm birth
• Application advances of electromyometrial imaging (EMMI) and electromyography (EMG) in parturition research
• Novel methods employed in parturition research
• Novel tocolytic use in mono and combination therapy to mitigate preterm labor
• Novel clinical intervention methods for predicting and regulating the parturition
