Nervous system injury, including central nerve injury and peripheral nerve injury, often leads to the loss of patients' intelligence, motor and sensory functions, and brings a heavy burden to individuals and their families. The nervous system is composed of neural tissue, which includes neurons, astrocytes, oligodendrocytes, microglia and Schwann cells. The transmission of neural information between cells is realized through complex cross-talk. At present, the regulation and remodeling mechanism of each cell after nervous system injury is still unclear. In recent years, with the development of stem cell transplantation, smart biomaterials, brain computer interface ultrasound regulation and other novel neural regulation technologies, it has brought a dawn for the alternative and non-invasive treatment of post-traumatic injury. However, there is still a lack of efficient neural regulation strategies to meet the repair needs of neural network remodeling after nervous system injury.
This Research Topic aims to explore the adjustability and plasticity of neurons and various neuroglial cells after nervous system injury, excavate the latest technologies of stem cell, biomaterials, biological agents, light/magnetic/electrical stimulation and brain computer interface to regulate the post injury nervous system and reshape the damaged neural circuit. Original research and review containing the above contents are highly expected.
The scope of this Research Topic mainly includes:
- To investigate the morphological and functional changes of neurons in the pathological states of brain, spinal cord and peripheral nerve injury;
- To explore the possible molecular mechanism of reconnecting neurons after brain, spinal cord and peripheral nervous system injury;
- To study the role of astrocytes, oligodendrocytes, microglia and Schwann cells in neural regulation and plasticity after injury;
- Looking for novel and innovation treatment methods to improve the repair ability after nerve injury, such as stem cell or biomaterial transplantation, exercise training, light stimulation, magnetic stimulation and electrical stimulation;
- To explore the possibility of using the latest stem cell, biomaterials, biological agents, light/magnetic/electrical stimulation techniques to regulate the damaged neural circuit, including its role in the activation, remodeling and pruning of the neural circuit.
Nervous system injury, including central nerve injury and peripheral nerve injury, often leads to the loss of patients' intelligence, motor and sensory functions, and brings a heavy burden to individuals and their families. The nervous system is composed of neural tissue, which includes neurons, astrocytes, oligodendrocytes, microglia and Schwann cells. The transmission of neural information between cells is realized through complex cross-talk. At present, the regulation and remodeling mechanism of each cell after nervous system injury is still unclear. In recent years, with the development of stem cell transplantation, smart biomaterials, brain computer interface ultrasound regulation and other novel neural regulation technologies, it has brought a dawn for the alternative and non-invasive treatment of post-traumatic injury. However, there is still a lack of efficient neural regulation strategies to meet the repair needs of neural network remodeling after nervous system injury.
This Research Topic aims to explore the adjustability and plasticity of neurons and various neuroglial cells after nervous system injury, excavate the latest technologies of stem cell, biomaterials, biological agents, light/magnetic/electrical stimulation and brain computer interface to regulate the post injury nervous system and reshape the damaged neural circuit. Original research and review containing the above contents are highly expected.
The scope of this Research Topic mainly includes:
- To investigate the morphological and functional changes of neurons in the pathological states of brain, spinal cord and peripheral nerve injury;
- To explore the possible molecular mechanism of reconnecting neurons after brain, spinal cord and peripheral nervous system injury;
- To study the role of astrocytes, oligodendrocytes, microglia and Schwann cells in neural regulation and plasticity after injury;
- Looking for novel and innovation treatment methods to improve the repair ability after nerve injury, such as stem cell or biomaterial transplantation, exercise training, light stimulation, magnetic stimulation and electrical stimulation;
- To explore the possibility of using the latest stem cell, biomaterials, biological agents, light/magnetic/electrical stimulation techniques to regulate the damaged neural circuit, including its role in the activation, remodeling and pruning of the neural circuit.