Structure-based drug design for diagnosis and treatment of neurological diseases

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Editorial

24 January 2017

Editorial: Structure-Based Drug Design for Diagnosis and Treatment of Neurological Diseases

Rona R. Ramsay

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Giuseppe Di Giovanni

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Giuseppe Di Giovanni

Department of Medical and Surgical Science, University of Magna Graecia

University of St Andrews

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Monoamine neurotransmitters such as dopamine, noradrenaline, histamine and serotonin play a central role in the pathophysiology of major neuropsychiatric illnesses, such as anxiety and mood disorders, schizophrenia, autism-spectrum disorders, Parkinson’s disease, epilepsy, and dementias. The aim of this Research Topic is to highlight interdisciplinary research using drug design, data-mining, structure-based drug design, medicinal chemistry and biological investigation in vitro and in vivo disease models, with input from behavioral and genetic studies. In this issue we encourage submissions of basic and/or clinical studies and review papers that summarize current knowledge and point out important deficiencies in our current understanding of the important monoamines systems.

Monoamine neurotransmitters such as dopamine, noradrenaline, histamine and serotonin play a central role in the pathophysiology of major neuropsychiatric illnesses, such as anxiety and mood disorders, schizophrenia, autism-spectrum disorders, Parkinson’s disease, epilepsy, and dementias. The aim of this Research Topic is to highlight interdisciplinary research using drug design, data-mining, structure-based drug design, medicinal chemistry and biological investigation in vitro and in vivo disease models, with input from behavioral and genetic studies. In this issue we encourage submissions of basic and/or clinical studies and review papers that summarize current knowledge and point out important deficiencies in our current understanding of the important monoamines systems.

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Editors

Giuseppe Di Giovanni

Department of Medical and Surgical Science, University of Magna Graecia

University of St Andrews

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146,188 Total views

109,078 Article views

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Frontiers in Neuroscience

Neuropharmacology

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Frontiers in Pharmacology

Neuropharmacology

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Frontiers in Psychiatry

Neuropharmacology

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Frontiers in Neurology

Neuropharmacology

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