About this Research Topic
The objective of this topic is to raise awareness of the long-term effects of viral infections in patients and to re-evaluate the way viral infections are treated and described. Traditional virus research is primarily focused on the direct mechanisms of viral infection, viral replication and the host immune response. Changes in cellular trafficking, cellular activity and metabolism have not yet been sufficiently researched due to technical limitations and the lack of well-established model systems. Recent developments, for instance the development of novel viral expression systems, new fluorophores for specific organelle labelling and novel monitoring approaches for cell characterization, open the field for new experimental approaches to characterize virus-cell interactions in more detail. These new approaches and findings should be addressed in this research topic.
This research topic welcomes contributions addressing the below listed themes. We welcome all kinds of submissions including Original Research Articles, Reviews, Opinions and Communications.
• Virus-induced changes in cellular trafficking
• Modulation in receptor and channel activity
• Metabolic modulation
• Rearrangement of cellular structures
• Modulation of apoptosis, necrosis and inflammation
• Virus-induced changes in cellular gene expression and protein production
Keywords: Virus, signaling, immune response, apoptosis, metabolism
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.