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Physical exercise has demonstrated positive effects on preventing and ameliorating a wide range of neuropsychiatric and neurodegenerative disorders, such as depression, anxiety, autism spectrum disorder, Alzheimer’s disease, Parkinson’s disease, etc. Neuroendocrinology provides an important perspective for ...

Physical exercise has demonstrated positive effects on preventing and ameliorating a wide range of neuropsychiatric and neurodegenerative disorders, such as depression, anxiety, autism spectrum disorder, Alzheimer’s disease, Parkinson’s disease, etc. Neuroendocrinology provides an important perspective for revealing the mechanism of exercise intervention. However, many changes in neuroendocrine system caused by physical exercise may simply be correlative rather than causative. Therefore, one of the main challenges will be to distinguish the functional mediators from modulators with respect to therapeutic effects of exercise. Good knowledge of these conditions should provide better understanding on neuroendocrine mechanisms, offer extensive opportunities for developing new and highly specific drugs, and reveal potential new approaches for the prevention and treatment of neuropsychiatric disorders.

We invite authors to contribute original research articles as well as review articles that contribute to understanding the neuroendocrine mechanism underlying neuropsychiatric disorders, and identify the biomarkers, molecular mediators or potential drug targets focused on the regulatory effects of physical exercise on the neuroendocrine system.

Potential topics include, but are not limited to:
- Exercise and functional adaptation of neuroendocrine system at molecular, cellular and organic levels
- Biomarkers of exercise effects on neuroendocrine system
- Key neuroendocrine factors mediating exercise effects on brain health
- Novel techniques and data analysis to investigate the neuroendocrine system integration network of exercise effects on brain health
- Structural biology of neuroendocrine factors mediating exercise effects on brain health
- Potential therapeutic targets for drug development based on the regulatory effects of exercise on the neuroendocrine system

Keywords: Neuroendocrinology, Physical Exercise, Neuropsychiatric Disorders, Molecular Mediators, Therapeutic Targets


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