Microbial infections can be otitis, angina, skin infections (paronychia, abscess, etc.), diarrhoea, urinary and genital infections. The prescription of antibiotics may be necessary to effectively fight against the microbe involved. The extensive and prolonged use of antibiotics, both in humans and in animals, has profoundly modified the microbial ecology. The overconsumption of antibiotics has resulted in a selective pressure by eliminating susceptible microbes, in turn favouring the development of antibiotic-resistant strains. The emergence of this resistance was initially countered by the development of new antibiotics. However, the lack of research momentum and the reduction in the number of new molecules available today threaten our “antibiotic capital”. This phenomenon of antibiotic resistance is even more worrying as it now concerns all pathogenic microorganisms.
The emergence of antibiotic resistant microorganisms complicates the treatment of ill patients and has become a significant public health threat. Numerous reports have been published by learned societies, government agencies and intergovernmental bodies, with advice to use antibiotics less frequently and more effectively, ensuring cross-infection is avoided, in order to reduce the need for antibiotic therapy. Despite these recommendations, microbial multi-resistance has increased. There is now a real concern to find new safe and effective anti-microbial agents. Recent advances in synthetic and isolation methodologies have increased the range of antimicrobial compounds. Further development in antimicrobial drug discovery is essential to combat the ever-growing multi-resistant strains.
This Research Topic aims to assess current and prospective research relating to all agents with anti-microbial activities. We welcome the following article types:
- Original research
- Systematic review
- Methods
- Review
- Mini review
- Hypothesis and Theory
- Perspective
- Clinical Trial
- Brief research report
- Study Protocol
Microbial infections can be otitis, angina, skin infections (paronychia, abscess, etc.), diarrhoea, urinary and genital infections. The prescription of antibiotics may be necessary to effectively fight against the microbe involved. The extensive and prolonged use of antibiotics, both in humans and in animals, has profoundly modified the microbial ecology. The overconsumption of antibiotics has resulted in a selective pressure by eliminating susceptible microbes, in turn favouring the development of antibiotic-resistant strains. The emergence of this resistance was initially countered by the development of new antibiotics. However, the lack of research momentum and the reduction in the number of new molecules available today threaten our “antibiotic capital”. This phenomenon of antibiotic resistance is even more worrying as it now concerns all pathogenic microorganisms.
The emergence of antibiotic resistant microorganisms complicates the treatment of ill patients and has become a significant public health threat. Numerous reports have been published by learned societies, government agencies and intergovernmental bodies, with advice to use antibiotics less frequently and more effectively, ensuring cross-infection is avoided, in order to reduce the need for antibiotic therapy. Despite these recommendations, microbial multi-resistance has increased. There is now a real concern to find new safe and effective anti-microbial agents. Recent advances in synthetic and isolation methodologies have increased the range of antimicrobial compounds. Further development in antimicrobial drug discovery is essential to combat the ever-growing multi-resistant strains.
This Research Topic aims to assess current and prospective research relating to all agents with anti-microbial activities. We welcome the following article types:
- Original research
- Systematic review
- Methods
- Review
- Mini review
- Hypothesis and Theory
- Perspective
- Clinical Trial
- Brief research report
- Study Protocol
