Glaucoma is one of the leading causes of global irreversible blindness. It is characterized by a progressive loss of retinal ganglion cells with corresponding optic nerve alterations and visual field loss. The pathophysiology of glaucoma is multifactorial and there are several clinical phenotypes. Diagnosis ...
Glaucoma is one of the leading causes of global irreversible blindness. It is characterized by a progressive loss of retinal ganglion cells with corresponding optic nerve alterations and visual field loss. The pathophysiology of glaucoma is multifactorial and there are several clinical phenotypes. Diagnosis of glaucoma is not always straightforward. Glaucoma slowly damages the eyes causing irreversible injury before there is any vision loss, this implies that a large number of glaucoma remain undiagnosed, leading to blindness. Elevated intraocular pressure (IOP) is recognized as a major risk factor for the development and progression of glaucoma and lowering IOP is currently the primary strategy of treating the disease. However, nowadays, new medical treatment strategies, such as neuroprotectors, or para surgical or surgical treatments have been proposed. Numerous clinical trials evaluating either medical, surgical, or behavioral intervention are being conducted around the world to study glaucoma aiming of improving its diagnosis, management, and treatment.
This Research Topic focuses on the very latest discoveries in the field of glaucoma, emphasizing novel advances in pathophysiology, diagnosis, patient treatment and rehabilitation in order to gain a better understanding of the disease.
These topics will welcome but are not limited to the following:
- Novel mechanisms and their biomarkers;
- New clinical therapeutic concepts;
- Artificial intelligence in glaucoma i.e. detection;
- Application of artificial intelligence in glaucoma diagnosis e follow-up;
- New targets for therapy;
- Advanced medical devices, pharmacological options or surgical strategies that could be used in clinical and surgical practice.
Keywords:
Glaucoma, neurodegeneration, glaucoma diagnosis, glaucoma treatment, retinal ganglion cells, intraocular pressure
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.