About this Research Topic
Chronic ischemic cerebrovascular disease (CICD) defines as all series of cerebrovascular disorders including large vessel and small vessel angiopathy, which is a common cause of ischemic stroke and cognitive dysfunction. Although complex pathology and high rates of morbidity make it challenging to treat, new clinical evidence continues to emerge on a deepening acknowledgment of CICD. Currently, basic and clinical research on CICD containing new-type biomarkers, application of neuroimaging techniques, and modified treatment accelerate the understanding of the disease. Besides, recent researching hotspots of CICD focus on studies about advanced brain function like cognitive performance, which is increasingly recognized as a risk factor for silent brain infarctions and dementia.
In this research topic, we aim to highlight the current progression in the diagnosis and management of chronic ischemic cerebrovascular disease, including carotid artery stenosis to occlusion, vertebra-basilar artery stenosis to occlusion, atherosclerotic intracranial artery stenosis to occlusion, moyamoya vasculopathy, cerebral small vessel disease, etc. Relative research about neuroimaging methods, biomarkers, novel evaluating techniques, advanced brain functions like cognition, as well as various kinds of treatments are welcomed in this topic.
Topics of interest include, but are not limited to following fields:
- Basic studies of neuroimaging biomarkers, pathophysiology and epidemiology of all kinds of chronic ischemic cerebrovascular disease.
- Clinical research of evaluating techniques including magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), positron emission tomography (PET), electroencephalography/ magnetoencephalography (EEG/MEG), functional near-infrared spectroscopy (fNIRs), etc. Besides, CICD-related advanced brain function studies like vascular cognitive impairment by means of imageomics or connectomics are also welcomed;
- Clinical evidence for the effectiveness and functional outcome of novel operative techniques, such as modified carotid endarterectomy or carotid artery stenting, intracranial artery angioplasty or stent implantation, bypass surgery and hybrid operations in the treatment of chronic ischemic cerebrovascular disease from single or multiple centers;
- Development and application of rehabilitation measures for the improvement of managing the chronic ischemic cerebrovascular disease;
- Endovascular management of chronic carotid occlusion.
Clinical research, meta-analysis, and literature review, preferably systematic, are welcome.
In this research topic, we aim to highlight the current progression in the diagnosis and management of chronic ischemic cerebrovascular disease, including carotid artery stenosis to occlusion, vertebra-basilar artery stenosis to occlusion, atherosclerotic intracranial artery stenosis to occlusion, moyamoya vasculopathy, cerebral small vessel disease, etc. Relative research about neuroimaging methods, biomarkers, novel evaluating techniques, advanced brain functions like cognition, as well as various kinds of treatments are welcomed in this topic.
Topics of interest include, but are not limited to following fields:
- Basic studies of neuroimaging biomarkers, pathophysiology and epidemiology of all kinds of chronic ischemic cerebrovascular disease.
- Clinical research of evaluating techniques including magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), positron emission tomography (PET), electroencephalography/ magnetoencephalography (EEG/MEG), functional near-infrared spectroscopy (fNIRs), etc. Besides, CICD-related advanced brain function studies like vascular cognitive impairment by means of imageomics or connectomics are also welcomed;
- Clinical evidence for the effectiveness and functional outcome of novel operative techniques, such as modified carotid endarterectomy or carotid artery stenting, intracranial artery angioplasty or stent implantation, bypass surgery and hybrid operations in the treatment of chronic ischemic cerebrovascular disease from single or multiple centers;
- Development and application of rehabilitation measures for the improvement of managing the chronic ischemic cerebrovascular disease;
- Endovascular management of chronic carotid occlusion.
Clinical research, meta-analysis, and literature review, preferably systematic, are welcome.
Keywords: Chronic Ischemic Cerebrovascular Disease, Brain Function, Diagnosis, Treatment, Neuroimaging Biomarker
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