This Research Topic is part of the 15 Year Anniversary of Cellular Neuroscience series, organized in collaboration with the Neuroscience portfolio at Frontiers. This initiative celebrates the journal's anniversary by highlighting influential areas of research and promoting discussion on recent advances in astrocyte biology, specifically their significant role in neurotransmission.Astrocytes, traditionally considered support cells, are now recognized as key players in shaping neurotransmission and neuronal communication. This article collection seeks to deepen our understanding of astrocytic functions and their impact on neurotransmission. We invite contributions in the form of Original Research, Reviews, Mini Reviews, and Perspectives covering, but not limited to, the following themes:The involvement of astrocytes in maintaining and modulating glutamatergic and GABAergic neurotransmission.- Astrocytic mitochondrial metabolism and its regulatory effects on neurotransmission.- NMDA receptors in astrocytes: implications for neurotransmission and astrocytic homeostasis.- Functional heterogeneity of astrocytes and its significance in shaping neurotransmission.- Astrocytic transport mechanisms involved in neurotransmission (e.g., glutamate and GABA transport).- Astrocyte interactions with microglia and other non-neuronal cells in the context of neurotransmission.- Astrocytic sodium signaling and its influence on neurotransmission.- Astrocyte-neuron metabolic interactions and their roles in modulating brain activity.- Astrocytes as critical regulators of synaptic plasticity.- Astrocytic calcium signaling and gliotransmitter release: their impact on synaptic transmission and plasticity.
This Research Topic is part of the 15 Year Anniversary of Cellular Neuroscience series, organized in collaboration with the Neuroscience portfolio at Frontiers. This initiative celebrates the journal's anniversary by highlighting influential areas of research and promoting discussion on recent advances in astrocyte biology, specifically their significant role in neurotransmission.Astrocytes, traditionally considered support cells, are now recognized as key players in shaping neurotransmission and neuronal communication. This article collection seeks to deepen our understanding of astrocytic functions and their impact on neurotransmission. We invite contributions in the form of Original Research, Reviews, Mini Reviews, and Perspectives covering, but not limited to, the following themes:The involvement of astrocytes in maintaining and modulating glutamatergic and GABAergic neurotransmission.- Astrocytic mitochondrial metabolism and its regulatory effects on neurotransmission.- NMDA receptors in astrocytes: implications for neurotransmission and astrocytic homeostasis.- Functional heterogeneity of astrocytes and its significance in shaping neurotransmission.- Astrocytic transport mechanisms involved in neurotransmission (e.g., glutamate and GABA transport).- Astrocyte interactions with microglia and other non-neuronal cells in the context of neurotransmission.- Astrocytic sodium signaling and its influence on neurotransmission.- Astrocyte-neuron metabolic interactions and their roles in modulating brain activity.- Astrocytes as critical regulators of synaptic plasticity.- Astrocytic calcium signaling and gliotransmitter release: their impact on synaptic transmission and plasticity.