Advancing Precision Medicine in Acute Stroke Care: Personalized Treatment Strategies and Outcomes

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183

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articles

Advancing Precision Medicine in Acute Stroke Care: Personalized Treatment Strategies and Outcomes

59.5K

views

183

authors

20

articles

Editorial

11 November 2025

Editorial: Advancing precision medicine in acute stroke care: personalized treatment strategies and outcomes

Mohamed F. Doheim

,

Nirav Bhatt

,

Alhamza R. Al-Bayati

,

Jean-Claude Baron

and

Joao Brainer Clares de Andrade

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Editors

4

Mohamed F Doheim

University of Pittsburgh Medical Center

Alhamza R. Al-Bayati

University of Pittsburgh Medical Center

Joao Brainer Clares Andrade

Federal University of São Paulo

Nirav Bhatt

University of Pittsburgh

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About

Precision medicine in the acute care of stroke has undergone significant advancements, particularly since 2015, when five pivotal trials demonstrated the safety and efficacy of endovascular treatment for acute ischemic stroke within the early treatment window. This marked a transformative shift in stroke management, offering new hope for improved patient outcomes. By 2018, further trials extended this evidence to a broader time window, yet these studies primarily concentrated on proximal large vessel occlusions in the anterior circulation, leaving a substantial portion of potential patients unaddressed. Recent research efforts have sought to expand the scope of care, exploring diverse patient cohorts and treatment paradigms. Despite these advancements, there remains a critical need to refine and personalize treatment strategies to optimize outcomes for each patient, taking into account their unique clinical, demographic, and imaging characteristics.

This Research Topic aims to consolidate a wide array of perspectives on precision medicine in the acute care of stroke, with the objective of providing a comprehensive overview of the latest developments in the field. The focus is on identifying the most beneficial treatment approaches for individual patients, considering their distinct inputs. By addressing specific questions related to patient management and testing hypotheses about personalized treatment strategies, this collection seeks to advance the understanding and application of precision medicine in stroke care.

To advance insights within precision medicine for acute stroke care, we welcome articles addressing, but not limited to, the following themes:
• Management approaches based on demographic characteristics of acute stroke patients.
• Clinical characteristics influencing treatment decisions and outcomes.
• Imaging characteristics that guide personalized treatment strategies.
• Primary and secondary studies exploring novel paradigms in stroke management.
• Comparative analyses of traditional versus precision medicine approaches in stroke care.

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Editors

Mohamed F Doheim

University of Pittsburgh Medical Center

Alhamza R. Al-Bayati

University of Pittsburgh Medical Center

Joao Brainer Clares Andrade

Federal University of São Paulo

Nirav Bhatt

University of Pittsburgh

Impact

59,488 Total views

42,930 Article views

13,418 Article downloads

3,140 Topic views

Published In

Frontiers in Medicine

Intensive Care Medicine and Anesthesiology

Frontiers in Neurology

Neurological Biomarkers

Frontiers in Stroke

Acute Stroke and Interventional Therapies

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