Molecular Mechanisms in Psychiatry 2023: Bipolar Disorder

Bipolar disorder is a complex mood disorder that affects millions of people worldwide. Despite the availability of treatments, many individuals with bipolar disorder continue to experience significant impairment in their daily lives. Recent research has identified several molecular mechanisms that contribute to the development and progression of bipolar disorder, including changes in neurotransmitter levels, alterations in cellular signaling pathways, and abnormalities in brain structure and function.

This Research Topic aims to bring together cutting-edge research on the molecular mechanisms of bipolar disorder from a variety of disciplines, including genetics, neurobiology, and pharmacology. We invite Original Research articles, Reviews, and Perspectives that cover the following topics:

- The genetic basis of bipolar disorder: recent advances in identifying genetic risk factors for bipolar disorder
- The role of neurotransmitters in bipolar disorder: the role of dopamine, serotonin, and other neurotransmitters in the pathophysiology of bipolar disorder
- Cellular signaling pathways in bipolar disorder: the role of intracellular signaling pathways, such as the cyclic AMP signaling pathway, in the development and progression of bipolar disorder
- Brain imaging studies of bipolar disorder: recent advances in identifying brain regions involved in bipolar disorder
- Emerging therapies for bipolar disorder: novel therapeutic targets and approaches for the treatment of bipolar disorder

We particularly encourage submissions that explore new avenues for the development of targeted therapies for bipolar disorder, and that highlight the translational potential of research on the molecular mechanisms of the disorder. With this Research Topic, we aim to provide a comprehensive overview of the current state of research on the molecular mechanisms of bipolar disorder, and to highlight new directions for future research.