Autoimmunity: novel insights and future perspectives

187.5K

views

235

authors

39

articles

Autoimmunity: novel insights and future perspectives

187.5K

views

235

authors

39

articles

Editorial

31 October 2025

Editorial: Autoimmunity: novel insights and future perspectives

Monica Neagu

,

Mihaela Adriana Ilie

,

Ancuta Mihai

and

Constantin Caruntu

1,698 views

0 citations

Editors

3

Constantin Caruntu

Carol Davila University of Medicine and Pharmacy

Monica Neagu

Victor Babes National Institute of Pathology (INCDVB)

Mihaela Adriana Ilie

Länssjukhuset i Kalmar

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About

Autoimmunity was, is and will be considered a hot topic in scientific research. One strong argument that maintains a high research interest in autoimmunity is represented by its dual facets: genetic and environmental. There are rapid advances in identification of various molecular players, from genes to autoantibodies, imposing the immune dysregulation that can lead to the development of diverse immune system diseases. Moreover, numerous endogenous or environmental triggers, such as chronic inflammation, medications, metabolites, viruses, bacteria, pollen, etc. are involved in the development of autoimmunity. The complexity of autoimmunity continues to amaze us, and each new discovery in this field paves the way for additional research directions that are crucial for advancing both our fundamental understanding and practical applications in clinical settings.

The immunological mechanisms that lead to autoimmune and autoinflammatory diseases are still not fully understood. The journey from emphasizing the immunological mechanisms and identifying autoantibodies as specific biomarkers to reaching the final diagnosis and establishing the therapeutic strategy, is difficult and generates a significant consumption of medical resources. Therefore, the scientific community must persist in its efforts to achieve important progresses in this major research area.

In this Research Topic, we aim to bring together the most recent and relevant scientific studies in the vast and complex field of autoimmunity. We invite investigators to contribute with original research and review articles bringing in the spotlight the recent findings regarding the immune system mechanisms, immunoregulatory proteins, genetic mutations that could be linked to the development of autoimmune diseases, as well the role of inflammation, viral triggers, and environmental risk factors in autoimmunity. Of particular interest for our Research Topic will be articles focused on the new target molecules involved in the development of immunomodulatory therapies.

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Editors

Constantin Caruntu

Carol Davila University of Medicine and Pharmacy

Monica Neagu

Victor Babes National Institute of Pathology (INCDVB)

Mihaela Adriana Ilie

Länssjukhuset i Kalmar

Coordinators

Ancuta MIHAI

Impact

187,482 Total views

134,426 Article views

50,423 Article downloads

2,633 Topic views

Published In

Frontiers in Immunology

Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

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With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

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