In recent years, important innovations have radically changed the guidelines for diagnosing and treating gynecological tumors. In cervical cancer, the LACC trial represents a milestone that radically modifies the surgical approach in early and advanced-stage cervical cancer. Nevertheless, there is still debate on the role of minimally invasive surgery for microscopic tumors or in FIGO stage IB1 after conization. Furthermore, more recent studies aimed at analyzing neoadjuvant chemotherapy in advanced cervical cancers compared to exclusive chemo-radiotherapy.
In Endometrial cancer patients, the new FIGO classification with the introduction of molecular characterization has sparked great concerns. If on the one hand, the new classification offers more details for personalizing treatment, on the other it does not appear feasible and available in all gynecological cancer centers around the world. Moreover, only in recent years, the adjuvant treatment for endometrial cancer has been based on molecular classification and prospective and consistent data are still missing.
In ovarian cancer, HOVHIPEC1 has shown impressive results in FIGO stage III ovarian cancer patients treatment undergoing interval debulking surgery after neoadjuvant chemotherapy. Despite this, there are still doubts about the selection of patients to undergo IDS versus PDS. In this regard, AI could provide important improvements. Furthermore, new fronts have opened up in the treatment of low-grade ovarian tumors. Finally, Hormone therapy seems to have a new role in ovarian cancer, cervical cancer, relapse and advanced endometrial cancer.
In light of these changes, the purpose of this topic is to select articles dealing with new indications in the diagnosis and treatment of gynecological tumors.
Keywords:
Gynecological Tumors, Ovarian Cancer, Surgical Treatment, Update, Endometrial Cancer, Gynecological Surgery
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
In recent years, important innovations have radically changed the guidelines for diagnosing and treating gynecological tumors. In cervical cancer, the LACC trial represents a milestone that radically modifies the surgical approach in early and advanced-stage cervical cancer. Nevertheless, there is still debate on the role of minimally invasive surgery for microscopic tumors or in FIGO stage IB1 after conization. Furthermore, more recent studies aimed at analyzing neoadjuvant chemotherapy in advanced cervical cancers compared to exclusive chemo-radiotherapy.
In Endometrial cancer patients, the new FIGO classification with the introduction of molecular characterization has sparked great concerns. If on the one hand, the new classification offers more details for personalizing treatment, on the other it does not appear feasible and available in all gynecological cancer centers around the world. Moreover, only in recent years, the adjuvant treatment for endometrial cancer has been based on molecular classification and prospective and consistent data are still missing.
In ovarian cancer, HOVHIPEC1 has shown impressive results in FIGO stage III ovarian cancer patients treatment undergoing interval debulking surgery after neoadjuvant chemotherapy. Despite this, there are still doubts about the selection of patients to undergo IDS versus PDS. In this regard, AI could provide important improvements. Furthermore, new fronts have opened up in the treatment of low-grade ovarian tumors. Finally, Hormone therapy seems to have a new role in ovarian cancer, cervical cancer, relapse and advanced endometrial cancer.
In light of these changes, the purpose of this topic is to select articles dealing with new indications in the diagnosis and treatment of gynecological tumors.
Keywords:
Gynecological Tumors, Ovarian Cancer, Surgical Treatment, Update, Endometrial Cancer, Gynecological Surgery
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.